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Clinical Experiences with a Modified BFM Protocol in Childhood Acute Lymphoblastic Leukemia

  • F. Zintl
  • H. Malke
  • W. Plenert
Conference paper
Part of the Haematology and Blood Transfusion / Hämatologie und Bluttransfusion book series (HAEMATOLOGY, volume 29)

Abstract

The most important problem in current therapy of childhood acute lymphoblastic leukemia (ALL) is a failure in over one-half of patients. We were unable to increase the failure-free survival of children with high risk ALL by a ten-drug regimen (modified LSA2L2) above 30% at 6 years [1].

Keywords

Acute Lymphoblastic Leukemia Childhood Acute Lymphoblastic Leukemia Induction Protocol Continuous Complete Remission Initial White Blood Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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    Zintl F, Hermann J, Katenkamp D, Malke H, Plenert W (1983) Results of LSA2L2 therapy in children with high risk acute lymphoblastic leukemia and non-Hodgkin’s lymphoma. In: Neth R, Gallo RC, Greaves MF, Moore MAS, Winkler K (eds) Modern trends in human leukemia, vol V. Springer, Berlin Heidelberg New York Tokyo, pp 62–66Google Scholar
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    Riehm H, Henze G, Langermann HJ (1981) Multizentrische Therapiestudie BFM 81 zur Behandlung der akuten lymphoblastischen Leukämie im Kindes- und Jugendalter. Studienprotokoll, 1981Google Scholar
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    Henze G, Langermann HJ, Fengler R et al. (1982) Therapiestudie BFM 79/81 zur Behandlung der akuten lymphoblastischen Leukämie bei Kindern und Jugendlichen: intensivierte Reinduktionstherapie für Patientengruppen mit unterschiedlichem Rezidivrisiko. Klin Pädiatr 194: 195–203PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1985

Authors and Affiliations

  • F. Zintl
  • H. Malke
  • W. Plenert

There are no affiliations available

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