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Clinical Experiences with a Modified BFM Protocol in Childhood Acute Lymphoblastic Leukemia

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Modern Trends in Human Leukemia VI New Results in Clinical and Biological Research Including Pediatric Oncology

Part of the book series: Haematology and Blood Transfusion / Hämatologie und Bluttransfusion ((HAEMATOLOGY,volume 29))

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Abstract

The most important problem in current therapy of childhood acute lymphoblastic leukemia (ALL) is a failure in over one-half of patients. We were unable to increase the failure-free survival of children with high risk ALL by a ten-drug regimen (modified LSA2L2) above 30% at 6 years [1].

Universitäts-Kinderklinik Jena, Abt. Hämatologie/Onkologie/Immunologie, Kochstraß 2, 6900 Jena, GDR

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References

  1. Zintl F, Hermann J, Katenkamp D, Malke H, Plenert W (1983) Results of LSA2L2 therapy in children with high risk acute lymphoblastic leukemia and non-Hodgkin’s lymphoma. In: Neth R, Gallo RC, Greaves MF, Moore MAS, Winkler K (eds) Modern trends in human leukemia, vol V. Springer, Berlin Heidelberg New York Tokyo, pp 62–66

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  2. Riehm H, Gadner H, Henze G, Langermann HJ, Odenwald E (1980) The Berlin childhood acute lymphoblastic leukemia therapy study, 1970–1976. Am J Ped Hematol Oncol 2: 299–306

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  3. Riehm H, Henze G, Langermann HJ (1981) Multizentrische Therapiestudie BFM 81 zur Behandlung der akuten lymphoblastischen Leukämie im Kindes- und Jugendalter. Studienprotokoll, 1981

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  4. Langermann HJ, Henze G, Wulf M, Riehm H (1982) Abschätzung der Tumorzellmasse bei der akuten lymphoblastischen Leukämie im Kindesalter: prognostische Bedeutung und praktische Anwendung. Klin Pädiatr 194: 209–213

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  5. Henze G, Langermann HJ, Fengler R et al. (1982) Therapiestudie BFM 79/81 zur Behandlung der akuten lymphoblastischen Leukämie bei Kindern und Jugendlichen: intensivierte Reinduktionstherapie für Patientengruppen mit unterschiedlichem Rezidivrisiko. Klin Pädiatr 194: 195–203

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Authors
  1. F. Zintl
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  2. H. Malke
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  3. W. Plenert
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Editor information

Editors and Affiliations

  1. Medizinische Klinik, Abteilung für klinische Chemie, Universitäts-Krankenhaus Eppendorf, Martinistraße 52, 2000, Hamburg 20, Germany

    Rolf Neth

  2. Laboratory of Tumor Cell Biology, National Cancer Institute, Bethesda, MD, 20205, USA

    Robert C. Gallo

  3. Leukaemia Research Fund Centre, Chester Beatty Laboratories, Institute of Cancer Research, Fulham Road, London, SW3 6JB, UK

    Melvyn F. Greaves

  4. Abteilung für Hämatologie und Onkologie, Universitäts-Kinderklinik, Martinistraße 52, 2000, Hamburg 20, Germany

    Gritta Janka

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© 1985 Springer-Verlag Berlin Heidelberg

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Zintl, F., Malke, H., Plenert, W. (1985). Clinical Experiences with a Modified BFM Protocol in Childhood Acute Lymphoblastic Leukemia. In: Neth, R., Gallo, R.C., Greaves, M.F., Janka, G. (eds) Modern Trends in Human Leukemia VI New Results in Clinical and Biological Research Including Pediatric Oncology. Haematology and Blood Transfusion / Hämatologie und Bluttransfusion, vol 29. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70385-0_21

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  • DOI: https://doi.org/10.1007/978-3-642-70385-0_21

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-15329-0

  • Online ISBN: 978-3-642-70385-0

  • eBook Packages: Springer Book Archive

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