Skip to main content

Ultrafiltration During Cardiopulmonary Bypass

  • Chapter
Arteriovenous Hemofiltration
  • 54 Accesses

Abstract

Crystalloid prime with hemodilution has been a great advantage to cardiac surgeons, for in addition to decreasing blood requirements it has also resulted in improved pulmonary and renal function [1]. Postoperative weight gain and an increase of up to 33% in the measured extracellular fluid space [2] are the disadvantages of dilution perfusion. In most patients this excess water is well tolerated and rapidly excreted. Certainly in renal failure patients, this excess fluid load may be detrimental. However, we are also interested in patients with severe preoperative fluid overload, in whom, even with adequate renal function, the additional water volume particularly in the lungs, may lead to organ dysfunction. We first set out to evaluate the use of ultrafiltration during cardiopulmonary bypass in a laboratory setting and have now instituted its use in a clinical setting. The following is a report of that experience.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

eBook
USD 16.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Lilleaasen P, Stokke O (1978) Moderate and extreme hemodilution in open heart surgery: fluid balance and acid-base studies. Ann Thorac Surg 25: 127–133

    Article  PubMed  CAS  Google Scholar 

  2. Breckenridge IM, Digerness SB, Kirklin JW (1970) Increased extracellular fluid after open intracardiac Operation. Surg Gynecol Obstet 131: 53–56

    PubMed  CAS  Google Scholar 

  3. Davis LE (1963) Treatment and management of burns. Veterinary Scope 8: 7–11

    Google Scholar 

  4. Pearce ML, Yamashita J, Beazell J (1965) Management of pulmonary edema. Circ Res 16: 482–488

    PubMed  CAS  Google Scholar 

  5. Holcroft JW, Turnkey DD (1974) Extravascular lung water following hemorrhagic shock in the baboon. Ann Surg 180: 480–487

    Article  Google Scholar 

  6. English TAH, Digerness S, Kirklin JW (1971) Changes in colloid osmotic pressure during and shortly after open intracardiac operation. J Thorac Cardiovasc Surg 61: 338–341

    PubMed  CAS  Google Scholar 

  7. Darup J, Bleese N, Kalmar P, Lute G, Pokar H, Polonius MJ (1979) Hemofiltration during extracorporeal circulation. Thorac Cardiovasc Surg 27: 227–230

    Article  PubMed  CAS  Google Scholar 

  8. Romagnoli A, Hocker J, Keats A, Milan J (1976) External hemoconcentration after deliberate hemodilution. In: Abstracts from the annual meeting of the American Society of Anesthesiology. Am Society of Anesthesiology, Park Ridge, p 2699.

    Google Scholar 

  9. Demling RH, Hick RE, Edmunds LH Jr (1976) Changes in extravascular lung water during veno venous perfusion. J Thorac Cardiovasc Surg 71: 291–294

    PubMed  CAS  Google Scholar 

  10. Utley JR, Wachtel C, Cain RB, Spaw EA, Collins JC, Stephens DB (1980) Effects of hypothermia, hemodilution, and pump oxygenation on organ water content, blood flow, and oxygen delivery and renal function. Ann Thorac Surg 31: 121–133

    Article  Google Scholar 

  11. Holcroft JW, Hopewell P, Sheldon GF, Lipanski A, Hoeffel J, Osborn JO (1973) Thermodilution for measurement of lung water: comparison with isotope and gravimetric methods. Circulation 48 [Suppl 4]: 447

    Google Scholar 

  12. Magilligan DJ Jr, Oyama C, Levin N (1981) Interstitial and intraalveolar pulmonary edema - reversal by ultrafiltration. Crit Care Med 9: 257

    Article  Google Scholar 

  13. Magilligan DJ Jr, Oyama C (1984) Ultrafiltration during cardiopulmonary bypass: Laboratory evaluation and initial clinical evaluation. Ann Thorac Surg 37: 33–39

    Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1985 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Magilligan, D.J. (1985). Ultrafiltration During Cardiopulmonary Bypass. In: Kramer, P. (eds) Arteriovenous Hemofiltration. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70370-6_26

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-70370-6_26

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-15317-7

  • Online ISBN: 978-3-642-70370-6

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics