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The Role of Human Class II Molecules in Activation of T4 Lymphocytes

  • Chapter
HLA Class II Antigens

Abstract

While B lymphocytes can bind antigen directly, T lymphocytes recognize antigen only when presented together with major histocompatibility complex (MHC)-en-coded class I or II molecules in the membrane of antigen-presenting cells (APC). This is called MHC restriction and was first shown in animal studies (see [5, 25] for references). The parts of the MHC molecule which are co-recognized together with antigen are often called restriction elements.

Work supported by grants from the Norwegian Cancer Society, The Norwegian Diabetes Society, and the University of Oslo

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Authors
  1. E. Qvigstad
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  2. Ø. Bruserud
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  3. E. Thorsby
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Editor information

Editors and Affiliations

  1. Blood Bank and Immunohematological Laboratory, Rikshospitalet, National Hospital, Pilestredet 32, N-0027, Oslo 1, Norway

    Bjarte G. Solheim (Director) (Director)

  2. Karolinska Institute, Department of Clinical Immunology, Huddinge Hospital, S-14186, Huddinge, Sweden

    Erna Møller

  3. Dept. of Microbiology and Immunology, New York Medical College, Valhalla, NY, 10595, USA

    Soldano Ferrone

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© 1986 Springer-Verlag Berlin Heidelberg

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Qvigstad, E., Bruserud, Ø., Thorsby, E. (1986). The Role of Human Class II Molecules in Activation of T4 Lymphocytes. In: Solheim, B.G., Møller, E., Ferrone, S. (eds) HLA Class II Antigens. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70367-6_28

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  • DOI: https://doi.org/10.1007/978-3-642-70367-6_28

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-70369-0

  • Online ISBN: 978-3-642-70367-6

  • eBook Packages: Springer Book Archive

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