Monoclonal Antibody Protection Against Pseudomonas aeruginosa
Biotechnology companies are isolating monoclonal antibodies against various bacterial products with the aim of utilizing them in prevention and therapy of infection. One that has received attention is the anti-lipid A monoclones for all gram-negative bacteria. Unfortunately, the early results have been quite disappointing. Our investigation was to see if some outer membrane proteins which are functionally conserved were also antigenically conserved and would provide a candidate antigen for a vaccine.
KeywordsPseudomonas Choline Phosphocholine
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