H+-ATPase and H+/Ion Antiporters of the Vacuolar Membrane of Saccharomyces Carlsbergensis Yeast

  • L. A. Okorokov
  • L. P. Lichko
  • T. V. Kulakovskaya


Various solutes are accumulated by yeast vacuoles (Matile 1978; Okorokov et al. 1980). It is suggested that transport systems of the vacuolar membrane create ion gradients across the yeast tonoplast (Okorokov et al. 1980) and regulate ion concentrations in the cytosol (Lichko et al. 1982). Nowadays there exist convincing evidences that the yeast tonoplast is equipped with the specific ATPase (Okorokov et al. 1982) operating as a proton pump (Kakinuma et al. 1981; Okorokov and Lichko 1983). Ohsumi and Anraku have been the first to present evidences that vesicles of the vacuolar membrane of S. cerevisiae possess arginine/H+ and Ca2+/H+ antiporters (Ohsumi and Anraku 1981; 1983).


ATPase Activity Anion Channel Vacuolar Membrane Vacuolar ATPase Yeast Vacuole 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1985

Authors and Affiliations

  • L. A. Okorokov
    • 1
  • L. P. Lichko
    • 1
  • T. V. Kulakovskaya
    • 1
  1. 1.Institute of Biochemistry and Physiology of MicroorganismsUSSR Academy of SciencesPushchinoUSSR

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