PAF-acether (Platelet Activating Factor)

  • B. Arnoux
  • C. Brink
  • J. Benveniste


When basophils, which were derived from sensitized rabbits, were challenged with a specific allergen a substance was extracted which was capable of aggregating rabbit platelets [3]. Since its initial detection it has been referred to as platelet activating factor (PAF), and more recently acetyl-glyceryl-ether-phosphorylcholine (AGEPC) or PAF-acether. The detection of this ubiquitous compound when various cells or organs are appropriately challenged has led to its acceptance as a pivotal molecule in a variety of pathophysiological conditions.


Alveolar Macrophage Platelet Activate Factor Rabbit Platelet Alveolar Macro Washed Rabbit Platelet 
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Copyright information

© Springer-Verlag, Berlin Heidelberg 1987

Authors and Affiliations

  • B. Arnoux
  • C. Brink
  • J. Benveniste

There are no affiliations available

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