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PAF-acether (Platelet Activating Factor)

  • B. Arnoux
  • C. Brink
  • J. Benveniste

Abstract

When basophils, which were derived from sensitized rabbits, were challenged with a specific allergen a substance was extracted which was capable of aggregating rabbit platelets [3]. Since its initial detection it has been referred to as platelet activating factor (PAF), and more recently acetyl-glyceryl-ether-phosphorylcholine (AGEPC) or PAF-acether. The detection of this ubiquitous compound when various cells or organs are appropriately challenged has led to its acceptance as a pivotal molecule in a variety of pathophysiological conditions.

Keywords

Alveolar Macrophage Platelet Activate Factor Rabbit Platelet Alveolar Macro Washed Rabbit Platelet 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag, Berlin Heidelberg 1987

Authors and Affiliations

  • B. Arnoux
  • C. Brink
  • J. Benveniste

There are no affiliations available

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