Abstract
Studies of central respiratory regulation disturbances (Haidmayer et al. 1982b) and esophageal motor functioning (Höllwarth 1979) in infants, which have been done independently of one another, called our attention to the frequent coincidence of apnea during sleep and gastroesophageal reflux (GER). Since both frequent and long periods of sleep apnea (Guilleminault and Ariagno 1977; Haidmayer et al. 1982a, b; Naeye 1977; Southall et al. 1980; Steinschneider 1972) as well as gastroesophageal reflux (Downing and Lee (1975; Herbst et al. 1978, 1979; Lawson 1981; Leape et al. 1977; Ramenofsky and Leape 1981) are associated with the sudden death syndrome (SIDS), we tried to establish the coincidence of both disorders quantitatively.
Supported by Grant No. 2883 from the “Fonds zur Förderung der wissenschaftlichen Forschung in Österreich”.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Althoff H (1980) Sudden infant death syndrome (SIDS). Forensic-medical experience, research and conclusions regarding a general medical problem. Fischer, Stuttgart
Ariagno RL, Guilleminault C (1982) Movement and gastroesophageal reflux in awake term infants with “near miss” SIDS, unrelated to apnea. J Pediatr 100:894–897
Brady JP, Ariagno RL, Watts JL, Goldmann SL, Dumpit FM (1978) Apnea, hypoxemia and aborted sudden infant death syndrome. Pediatrics 62:686–691
Downing SE, Lee JC (1975) Laryngeal chemosensitivity: a possible mechanism for sudden infant death. Pediatrics 55:640–649
Gabriel M, Witolla C, Albam M (1978) Sleep and aminophylline treatment of apnea in preterm infants. Eur J Pediatr 128:145–149
Guilleminault C, Ariagno R (1977) Sudden infant death syndrome. Bull Eur Physiopathol Respir 13:591–597
Haidmayer R, Kurz R, Kenner T, Wurm H, Pfeiffer KP (1982a) Physiological and clinical aspects of respiration control in infants with relation to the sudden infant death syndrome. Klin Wochenschr 60:9–18
Haidmayer R, Pfeiffer KP, Kenner T, Kurz R (1982b) Statistical evaluation of respiratory control in infants to assess possible risk for the sudden infant death syndrome (SIDS). Eur J Pediatr 138:145–150
Harned SH, Myracle J, Ferreiro J (1978) Respiratory suppression and swallowing from introduction of fluids into the laryngeal region of the lamb. Pediatr Res 12:1003–1009
Herbst JJ, Book LS, Bray PF (1978) Gastroesophageal reflux in the “near miss” sudden infant death syndrome. J Pediatr 92:73–75
Herbst JJ, Minton SD, Book LS (1979) Gastroesophageal reflux causing respiratory distress and apnea in newborn infants. J Pediatr 95:763–768
Höllwarth M (1979) Die Entwicklung der Speiseröhrenfunktion bei Neugeborenen — eine manometrische Studie. Z Kinderchir 27:201–215
Kurz R, Schneeweiß S, Haidmayer R, Kenner T, Pfeiffer KP (1983) Früherkennung zentraler Atemregulationsstörungen beim Säugling zur Vermeidung postoperativer Komplikationen. Klin Pädiatr 195:29–32
Lawson EE (1981) Prolonged central respiratory inhibition following reflux-induced apnea. J Appl Physiol 50:874–879
Leape LL, Holder TM, Franklin JD, Amoury RA, Asheraft KW (1977) Respiratory arrest in infants secondary to gastroesophageal reflux. Pediatrics 60:924–927
Lee JC, Stoll BJ, Downing SE (1977) Properties of the laryngeal chemoreflux in neonatal piglets. Am J Physiol 233 (1): R30–R36
Myers T, Milsap RL, Krauss AN, Auld PAM, Reidenberg MM (1980) Low-dose theophylline therapy in idiopathic apnea of prematurity. J Pediatr 96:99–103
Naeye RL (1977) The sudden infant death syndrome. Arch Pathol Lab Med 101:165–167
Pinkham JR, Beckwith JB (1970) Vocal cord lesions in the sudden infant death syndrome. In: Bergmann AB, Beckwith JB, Ray CG (eds) Proceedings of the 2nd international conference on causes of sudden infant death in infants. University of Washington Press, Seattle
Ramenofsky ML, Leape LL (1981) Continuous upper esophageal monitoring in infants and children with gastroesophageal reflux, pneumonia, and apneic spells. J Pediatr Surg 16: 374–378
Rigatto H (1977a) Ventilatory response to hypoxia. Semin Perinatol 1:357–362
Rigatto H (1977b) Apnea and periodic breathing. Semin Perinatol 1:375–381
Rigatto H (1977a) Ventilatory response to hypoxia. Semin Perinatol 1:357–362
Southall DP, Richards J, Brown DJ, Johnston PGB, De Swiet M, Shinebourne EA (1980) 24-hour tape recordings of ECG and respiration in the newborn infant with findings related to sudden death and unexplained brain damage in infancy. Arch Dis Child 55:7–16
Stark AR, Thach BT (1976) Mechanisms of airway obstruction leading to apnea in newborn infants. J Pediatr 89:982–985
Steinschneider A (1972) Prolonged apnea and the sudden infant death syndrome: clinical and laboratory observations. Pediatrics 50:646–654
Sutton D, Taylor EM, Lindemann RC (1978) Prolonged apnea in infant monkeys resulting from stimulation of superior laryngeal nerve. Pediatrics 61:519–527
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1985 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Kurz, R., Höllwarth, M., Fasching, M., Haidmayer, R., Pfeiffer, K.P., Kenner, T. (1985). Combined Disturbance of Respiratory Regulation and Esophageal Function in Early Infancy. In: Wurnig, P., Klos, I. (eds) Gastro-esophageal Reflux in Childhood Problems of Splenic Surgery in Childhood. Progress in Pediatric Surgery, vol 18. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70276-1_7
Download citation
DOI: https://doi.org/10.1007/978-3-642-70276-1_7
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-70278-5
Online ISBN: 978-3-642-70276-1
eBook Packages: Springer Book Archive