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Mononitrates pp 270-276 | Cite as

Double-Blind, Cross-Over Study on the Antianginal Efficacy of IS-5-MN and ISDN s.r., a Multicenter Trial

  • G. Steinorth
  • U. Seidel
  • M. Glocke
  • H. J. Überbacher
Part of the International Boehringer Mannheim Symposia book series (BOEHRINGER)

Abstract

The hemodynamic effects and the antianginal efficacy of isosorbide-5-mononitrate (IS-5-MN, ISMO 20) in comparison with slow-release isosorbide dinitrate (ISDN) have been demonstrated in a number of controlled studies [1, 3, 4].

Keywords

Coronary Heart Disease Angina Pectoris Isosorbide Dinitrate Angina Pectoris Attack Pretreatment Period 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Bödigheimer K, Nowak FG, Delius W (1981) Vergleichende invasive Untersuchung über die Wirkung von Isosorbid-5-Mononitrat und Isosorbiddinitrat bei chronischer Herzinsuffizienz. Med Welt 32/14a:543–547PubMedGoogle Scholar
  2. 2.
    Keenan RE: Guidelines for the Clinical Evaluation of Anti-Anginal Drugs. FDA 78–3047Google Scholar
  3. 3.
    Müller G, Hacker W, Schneider B (1983) Intra-individual Comparison of the Action of Equal Doses of Isosorbide-5-endomononitrate, Slow-release Isosorbide Dinitrate and Placebo in Patients with Coronary Heart Disease. Klin Wochenschr 61:409–416PubMedCrossRefGoogle Scholar
  4. 4.
    Reifart N, Reifart F, Kaltenbach M, Bussmann W-D (1981) Vergleich der antianginösen Wirksamkeit und Wirkdauer von oral verabreichtem Isosorbiddinitrat (ISDN), Isosorbid-2-Mononitrat (IS-2-MN) und Isosorbid-5-Mononitrat (IS-5-MN). Med Welt 32/14 a:524–526PubMedGoogle Scholar
  5. 5.
    Überbacher HJ, Glocke M, Abshagen U (1983) Langzeitverträglichkeit und koronartherapeutische Wirksamkeit von Isosorbid-5-Mononitrat — Offene Multicenter-Studie unter Praxis-Bedingungen mit ISMO 20. MMW125, 4:76–78Google Scholar
  6. 6.
    Überbacher HJ, Steinorth G, Glocke M, Abshagen U (1983) An open, long-term multi-centre study of the antianginal efficacy and safety of isosorbide-5-mononitrate at low doses in patients with coronary heart disease. Pharmatherapeutica 3, 5:331–341PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1985

Authors and Affiliations

  • G. Steinorth
  • U. Seidel
  • M. Glocke
  • H. J. Überbacher

There are no affiliations available

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