Skip to main content
SpringerLink
Log in

Paraneoplasien der Neoplasmen der Bronchien und der Lunge

  • Chapter
Tumoren der Atmungsorgane und des Mediastinums A

Part of the book series: Handbuch der inneren Medizin ((INNEREN 4,volume 4 / 4 / A))

  • 18 Accesses

Zusammenfassung

Viele Patienten mit einem Bronchialkarzinom leiden an uncharakteristischen Beschwerden wie Leistungsschwäche, Abgeschlagenheit, Inappetenz, Fieber und Gewichtsverlust. Im Gegensatz hierzu bestehen bei einer kleinen Anzahl von Bronchialkarzinomträgern mannigfaltige Symptome, die nicht im direkten Zusammenhang mit einer Tumorinfiltration stehen (Bariety et al. 1964; Daughtry et al. 1967; Mlczoch u. Schnetz 1973; Rassam u. Anderson 1975). Neben den direkten Zeichen des primären oder metastatischen Wachstums gibt es eine Reihe unspezifischer Wirkungen, die sich extrathorakal, aber nicht metastatisch bedingt manifestieren, jedoch als direkte Tumorfolge anzusehen sind. Gelegentlich treten daher paraneoplastische Syndrome bei okkultem Bronchialkarzinom zuerst in Erscheinung (Pate et al. 1960).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 54.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 69.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  • Amatruda TT, Mulrow PJ, Gallagher JG, Sawyer WH (1963) Carcinoma of the lung with inappropiate antidiuresis. N Engl J Med 269: 544–549

    PubMed  Google Scholar 

  • Amromin GD, Wang SK (1959) Degenerative verrucal endocardiosis and myocardial infarction: report of two cases associated with mucus-producing bronchogenic carcinoma. Ann Int 50: 1519–1529

    CAS  Google Scholar 

  • Andrews B, Arora NS, Shadforth MF, Goldberg STK, Davis IVJS (1981) The role of immune complexes in the pathogenesis of pleural effusions. Am Rev Respir Dis 124: 115

    Google Scholar 

  • Angel JH (1957) Pachydermo-Periostosis (Idiopathic Osteoarthropathy). Br Med J 11: 789–792

    Google Scholar 

  • Askergren A, Hilenius L (1964) Bronchial adenomas and the cardinoid syndrome. Acta Med Scand 175: 43–48

    PubMed  CAS  Google Scholar 

  • Ayvazian LF, Schneider B, Gewirtz G, Yalow RS (1975) Ectopic production of big ACTH in carcinoma of the lung: Its clinical usefulness as a biologic marker. Am Rev Respir Dis 111: 279–287

    Google Scholar 

  • Azzopardi JG, Beilau AR (1965) Carcinoid syndrome and oat-cell carcinoma of the bronchus. Thorax 20: 393–397

    Google Scholar 

  • Azzopardi JG, Whittaker RS (1969) Bronchial carcinoma and hypercalcemia. J Clin Pathol 22: 528–529

    Google Scholar 

  • Azzopardi JG, Williams ED (1968) Pathology of „endocrine“tumors associated with Cushing’s syndrome. Cancer 22: 274–286

    PubMed  CAS  Google Scholar 

  • Azzopardi JG, Freeman E, Poole G (1970) Endocrine and metabolic disorders in bronchial carcinoma. Br Med J IV: 528 - 530

    Google Scholar 

  • Bariety M, Coury C, Rulliere R (1964) Les syndromes paraneoplasiques dans le cancer bronchopulmonaire primitif. J Fr Med Chir Thorac 18: 19–68

    PubMed  CAS  Google Scholar 

  • Bartter FC, Schwartz WB (1967) The syndrome of inappropiate secretion of antidiuretic hormone. Am J Med 42: 790–806

    PubMed  CAS  Google Scholar 

  • Beck C, Burger HG (1972) Evidence for the presence of immunoreactive growth hormone in cancers of the lung and stomach. Cancer 30: 75–79

    PubMed  CAS  Google Scholar 

  • Beck C, Larkins RG, Martin TJ, Burger HG (1973) Stimulation of growth hormone release from superfused rat pituitary by extracts of hypothalamus and of human lung tumours. J Endocrinol 59: 325–333

    PubMed  CAS  Google Scholar 

  • Becker KL, Cottrell J, Moore CF, Winmacher JL, Matthews MJ, Katz S (1968) Endocrine studies in a patient with a gonadotropin-secreting bronchogenic carcinoma. J Clin Endocrinol Metab 28: 809–818

    PubMed  CAS  Google Scholar 

  • Becker KL, Snider RH, Silva OL, Moore CF (1978) Calcitonin heterogeneity in lung cancer and medullary thyroid cancer. Acta Endocrinol 89: 89–99

    PubMed  CAS  Google Scholar 

  • Bender RA, Hansen H (1974) Hypercalcemia in bronchogenic carcinoma. A prospective study of 200 patients. Ann Intern Med 80: 205–208

    PubMed  CAS  Google Scholar 

  • Benson RC, Riggs BL, Pickard BM, Arnaud CD (1974) Immunoreactive forms of circulating parathyroid hormone in primary and ectopic hyperparathyroidism. J Clin Invest 54: 175–181

    PubMed  Google Scholar 

  • Berde B (1969) Specifity of human neurohypophyseal hormone produced by ectopic hormone secretion. Coll Intern Centre Nat Rech Seien 177: 69–77

    Google Scholar 

  • Berg R (1949) Arthralgie as a first symptom of pulmonary lesions. Dis Chest 16: 483–487

    PubMed  Google Scholar 

  • Berman B (1963) Pulmonary hypertrophic osteoarthropathy. Arch Intern Med 112: 947–953

    PubMed  CAS  Google Scholar 

  • Bernheimer H, Ehringer H, Heistracher P, Kraupp O, Lachnit V, Obiditsch-Mayer I (1960) Biologisch aktives, nicht metastasierendes Bronchuskarzinoid mit Linksherzsyndrom. Wien Klin Wochenschr 72: 867–873

    Google Scholar 

  • Berson SA, Yalow RS (1966) Parathyroid hormone in plasma in adenomatous hyperparathyroidism, uremia and bronchogenic carcinoma. Science 154: 907–909

    PubMed  CAS  Google Scholar 

  • Berson SA, Yalow RS (1968) Immunochemical heterogenity of parathyroid hormone in plasma. J Clin Endocrinol Metab 28: 1037–1047

    PubMed  CAS  Google Scholar 

  • Björklund B (1980) On the nature an clinical use of tissue polypeptide antigen (TPA). Tumor Diagnostik 1: 9–20

    Google Scholar 

  • Blaha H, Birnberger A und C, Fliege KD (1973) Neurologische Manifestationen. In: Mlczoch F, Seidel H (Hrsg) Aktuelle Fragen der Lungenpathologie. Lunge und Stoffwechsel, Paraneoplasien, Atemtherapie. Thieme, Stuttgart

    Google Scholar 

  • Bloomfield GA, Holdawag JM, Corrin B, RatcHffe JG, Rees GM, Ellison M, Rees LH (1977) Lung tumours and ACTH production. Clin Endocrinol Metab 6: 95–104

    CAS  Google Scholar 

  • Bohan A, Peter JB (1975) Polymyositis and dermatomyositis. N Engl J Med 292: 344–347

    PubMed  CAS  Google Scholar 

  • Bower BF, Mason DM, Forsham PH (1963) Bronchogenic carcinoma with inappropiate antidiuretic activity in plasma and tumour. N Engl J Med 271: 934–938

    Google Scholar 

  • Bowman DM, Dube WJ, Levitt M (1975) Hypercalcemia in small cell (oatcell) carcinoma of the lung. Cancer 36: 1067–1071

    PubMed  CAS  Google Scholar 

  • Brain (1963) The neurological complications of neoplasms. Lancet 1: 179–184

    Google Scholar 

  • Braunstein GD, Vaitukaitis JL, Carbone MD, Ross GT (1973) Ectopic production of human chorionic gonadotropin by neoplasms. Ann Intern Med 78: 39–45

    PubMed  CAS  Google Scholar 

  • Breukelen FJ van, Bijvoet OL, Oosterom AT van (1979) Inhibition of osteolytic bone lesions by (3-amino-l-hydroxy-propylene)-1,1-diphosphonate ( APD ). Lancet 1: 803–805

    Google Scholar 

  • Brodie GN, Bliss D, Firkin BG (1970) Thrombocytopenic and carcinoma. Br Med J 1: 540–541

    PubMed  CAS  Google Scholar 

  • Brown WH (1928) A case of pluriglandular syndrome. „Diabetes of bearded women.“Lancet 11: 1022–1023

    Google Scholar 

  • Byrd B, Divertie MB, Spittell JA (1967) Bronchogenie carcinoma and thromboembolic disease. JAMA 202: 1019–1022

    PubMed  CAS  Google Scholar 

  • Carey VCI (1966) The incidence of hypercalcemia in association with bronchogenie carcinoma. Am Rev Respir Dis 93: 584–586

    PubMed  CAS  Google Scholar 

  • Cegla UH (1973) Zur Bedeutung und Pathogenese von Trommelschlegelfingern. Dtsch Med Wochenschr 98: 2143–2144

    PubMed  CAS  Google Scholar 

  • Cocking JB (1966) Thrombocytopenic purpura with bronchialcarcinoma. Postgrad Med J 42: 521–522

    PubMed  CAS  Google Scholar 

  • Cohen RB, Toll GT, Castleman B (1960) Bronchial adenomas in Cushing’s syndrome: Their relation to thymomas and oat cell carcinomas associated with hyperadrenocriticism. Cancer 13: 812–817

    Google Scholar 

  • Coombes RC, Hillyard C, Greenberg PB, Maclntyre J (1974) Plasma-immunoreactive-calcitonin in patients with nonthyroid tumours. Lancet 1: 85–86

    Google Scholar 

  • Coscia M, Brown RD, Miller M, Tanaka K, Nicholson WE, Parks KR, Orth DN (1977) Ectopic production of andidiuretic hormone (ADH), adrenocorticotrophic hormone ( ACTH) and beta- melanocyte stimulating hormone (ß-MSH.) by an oat cell carcinoma of the lung. Am J Med 62: 303–307

    Google Scholar 

  • Coury C (1960) Hippocratic fingers and hypertrophic osteoarthropathy. A study of 350 cases. Br J Dis Chest 54: 202–209

    PubMed  CAS  Google Scholar 

  • Croft PB, Wilkinson M (1963) Carcinomatous neuromyopathy. Its incidence in patients with carcinoma of the lung and carcinoma of the breast. Lancet 1: 184–188

    Google Scholar 

  • Cudkowitz L, Armstrong JB (1953) Finger clubbing and changes in the bronchial circulation. Br J Tuberc 47: 227–232

    Google Scholar 

  • Curth HO (1952) Significance of acanthosis nigricans. Arch Dermat Syph 66: 80–100

    CAS  Google Scholar 

  • Dabek JT (1974) Bronchial carcinoid tumour with acreomegaly in two patients. J Clin Endocrinol Metab 38: 329–333

    PubMed  CAS  Google Scholar 

  • Dailey JE, Marcuse PM (1969) Gonadotropin secreting giant cell carcinoma of the lung. Cancer 24: 388–396

    PubMed  CAS  Google Scholar 

  • Dambacher MA, Hunziker W, Fischer JA (1977) Die Bedeutung des Plasma-Calcitonins für die klinische Diagnostik. Dtsch Med Wochenschr 102: 1191–1193

    PubMed  CAS  Google Scholar 

  • Damon A, Holub DA, Melicow MM, Uson AC (1958) Polycythemia and renal carcinoma: report of ten new cases, two with long hematologic remission following nephrectomy. Am J Med 25: 182–197

    PubMed  CAS  Google Scholar 

  • Daughtry DC, Chesney JG, Spear HC, Gentsch TO, Larsen PB (1967) Unexplained systemic manifestations of malignant lung tumours. Dis Chest 52: 632–639

    PubMed  CAS  Google Scholar 

  • Davidson C (1972) Diabetes insipidus with an ACTH-secreting carcinoma of the bronchus. Br Med J 1: 287–288

    PubMed  CAS  Google Scholar 

  • Davis BB, Bloom ME, Field JB, Mintz DH (1969) Hyponatremia in pituary insufficiency. Metabolism 18: 821–832

    PubMed  CAS  Google Scholar 

  • Deftos LJ, Burton DW (1980) Immunohistological studies of nonthyroidal Calcitonin producing tumors. J Clin Endocrinol Metab 50: 1042–1045

    PubMed  CAS  Google Scholar 

  • Dennybrown D (1948) Primary sensory neuropathy with muscular changes associated with carcinoma. J Neurol Neurosurg Psychiatry 11: 73–87

    CAS  Google Scholar 

  • Eagan RT, Maurer LH, Forcier RJ, Tulloh M (1974) Small cell carcinoma of the lung-staging, paraneoplastic syndromes, treatment and survival. Cancer 33: 527–532

    PubMed  CAS  Google Scholar 

  • Eastridge CH, Hamman J (1965) Cushing’s syndrome in association with carcinoma of the respiratory tract. Ann Thorac Cardiovasc Surg 1: 151–158

    Google Scholar 

  • Eipper BA, Mains RE, Guenzi D (1976) High molecular weight forms of adrenocorticotropic hormone are glycoproteins. J Biol Chem 251: 4121–4126

    PubMed  CAS  Google Scholar 

  • Entwistle CC, Fentem PH, Jacobs A (1964) Red-cell aplasia with carcinoma of the bronchus. Br Med J 2: 1504–1506

    PubMed  CAS  Google Scholar 

  • Escovitz WE, Reingold IM (1961) Functioning malignant bronchial carcinoid with Cushing’s syn-drome and recurrent sinus arrest. Ann Intern Med 54: 1248–1259

    PubMed  CAS  Google Scholar 

  • Euler EC, Euler HH, Ammedick U, Konrad RM, Vollmer UJ (1978) CEA bei Fernmetastasierung. Med Welt 29: 828–830

    PubMed  CAS  Google Scholar 

  • Faiman CH, Colwell JA, Ryan RJ, Hershman JM, Shields TW (1967) Gonadotropin secretion from a bronchogenic carcinoma. Demonstration by radioimmunoassay. N Engl J Med 277: 1395–1399

    Google Scholar 

  • Flanagan P, Roeckel JE (1964) Giant cell carcinoma of the lung. Am J Med 36: 214–221

    PubMed  CAS  Google Scholar 

  • Flavell G (1956) Reversal of pulmonary osteoarthropathy by vagotomy. Lancet 1: 260–262

    Google Scholar 

  • Forschbach G (1973) Osteoarthropathie hypertrophiante pneumique - eine Paraneoplasie. In: Mlczoch F, Seidel H (Hrsg) Aktuelle Fragen der Lungenpathologie. Lunge und Stoffwechsel, Paraneoplasien, Atemtherapie. Thieme, Stuttgart, S 71–73

    Google Scholar 

  • Fry L (1962) Pseudohypoparathyroidism with carcinoma of the bronchus. Br Med J 1: 301–302

    PubMed  CAS  Google Scholar 

  • Fukase M (1978) Studies on calcitonin producing tumours. Med J Kobe Univ 37: 283–294

    CAS  Google Scholar 

  • Fusco FD, Rosen SW (1966) Gonadotropin-producing anaplastic large-cell carcinomas of the lung. N Engl J Med 275: 507–515

    PubMed  CAS  Google Scholar 

  • Gasser AB, Flury R, Senn HJ (1974) Therapie des Hypercalcämiesyndroms mit Mithramycin. Schweiz Med Wochenschr 204: 1792–1294

    Google Scholar 

  • Gault MH, Bilefsky R, Kinsella TD, Aronoff A (1965) Adrenocortical hyperfunction associated with bronchogenic carcinoma. Report of five cases. Can Med Assoc J 93: 1243–1249

    Google Scholar 

  • Gelfman NA (1961) Bronchogenic carcinoma with Cushing’s syndrome. A review with the report of an additional case. Am Rev Respir Dis 83: 555–562

    PubMed  CAS  Google Scholar 

  • Gewirtz G, Yalow RS (1974) Ectopic ACTH production in carcinoma of the lung. J Clin Invest 53: 1022–1023

    PubMed  CAS  Google Scholar 

  • Gewirtz G, Schneider B, Krüger DT, Yalow RS (1974) Big ACTH: conversion to biologically active ACTH by trypsin. J Clin Endocrinol 38: 59–63

    Google Scholar 

  • Ginsburg J (1958) Observations on the peripheral circulation in hypertrophic pulmonary osteoarthropathy. QJ Med 27: 335–352

    CAS  Google Scholar 

  • Gold P, Freedman SO (1965) Specific carcinoembryonic antigens of the human digestive system. J Exp Med 122: 467–481

    PubMed  CAS  Google Scholar 

  • Gowenlock AH, Platt DS, Campbell ACP, Wormsley KG (1964) Oat-cell carcinoma of the bronchus secreting 5-hydroxy-tryptophan. Lancet 1: 304–306

    PubMed  CAS  Google Scholar 

  • Gore JM, Appelbaum JS, Greene HL, Dexter L, Dalen JE (1982) Occult cancer in patientes with acute pulmonary embolism. Ann Intern Med 96: 556–560

    PubMed  CAS  Google Scholar 

  • Grant JL, MacDonald A, Brovender SR, Yankopoulos N (1965) Hypoadrenocorticotropism with hyponatremia resembling antidiuretic hormone excess. Ann Intern Med 63: 486–494

    PubMed  CAS  Google Scholar 

  • Greco FA, Kushner J (1974) Loss of symptoms of pulmonary hypertrophic osteoarthropathy after laparotomy. Ann Intern Med 81: 555–556

    PubMed  CAS  Google Scholar 

  • Greenberg PB, Beck C, Martin TJ, Burger HG (1972) Synthesis and release of human growth hormone from lung carcinoma in cell culture. Lancet 1: 350–352

    PubMed  CAS  Google Scholar 

  • Greene JG, Divertie MB, Brown AL, Lambert EH (1968) Small cell carcinoma of lung. Observations on four patients including one with a myasthenic syndrome. Arch Intern Med 122: 333–339

    Google Scholar 

  • Greenfield GB, Schorsch HA, Shkotmik A (1967) The various roentgen appearances of pulmonary hypertrophic osteoarthropathy. Am J Roentgenol 101: 927–931

    CAS  Google Scholar 

  • Gropp C, Havemann K, Lehmann FG (1978) Carcinoembryonic antigen and ferritin in patients with lung cancer before and during therapie. Cancer 42: 2802–2808

    PubMed  CAS  Google Scholar 

  • Gropp C, Havemann K, Scheuer A (1979) Zirkulierende Immunkomplexe beim Bronchialkarzinom. Klin Wochenschr 57: 401–409

    PubMed  CAS  Google Scholar 

  • Gropp C, Havemann K, Kalbfleisch H, Luster W, Soßtmann (1982) Antidiuretisches Hormon bei Patienten mit Bronchialkarzinom. Dtsch Med Wochenschr 107: 974–977

    CAS  Google Scholar 

  • Hamilton BP, Upton GV, Amatruda TT (1972) Evidence for the presence of neurophysin in tumours producing the syndrome of inappropriate antidiuresis. J Clin Endocrin Metab 35: 764–767

    CAS  Google Scholar 

  • Hantaan D, Rossier B, Zohlman R, Schrier R (1973) Rapid correction of hyponatremia in the syndrome of inappropriate secretion of antidiuretic hormone. Ann Intern Med 78: 870–875

    Google Scholar 

  • Hatch HB, Segaloff A, Ochsner A (1965) Adrenocortical function in bronchogenic carcinoma. Study of 100 patients. Ann Surg 161: 645–648

    PubMed  Google Scholar 

  • Hattorf M, Fukase M, Yoshimi H, Matsukura S, Imura H (1978) Ectopic production of human chorionic gonadotropin in malignant tumors. Cancer 42: 2328–2333

    Google Scholar 

  • Hattorf M, Imura H, Matsukura S, Yoshimoto V, Sekita K, Tomomatsu T, Kyogoku M, Kameya T (1979) Multiple-hormone producing lung carcinoma. Cancer 43: 2429–2437

    Google Scholar 

  • Havemann K, Gropp C (1979) Biological and immunological aspects of small cell carcinoma of the lung in relation to ectopic hormone production. Biomedicine 30: 186–194

    PubMed  CAS  Google Scholar 

  • Havemann K, Gropp C (1980) Ektope Hormonproduktion beim kleinzelligen Bronchialkarzinom. Biologische und immunologische Aspekte. Internist 21: 84–94

    Google Scholar 

  • Hayduk K, Kaufmann W (1972) Das Schwartz-Bartter-Syndrom. Dtsch Med Wochenschr 97: 1357–1360

    PubMed  CAS  Google Scholar 

  • Hayduk K, Kaufmann W (1973) Ektope paraneoplastische Endokrinopathien mit Störungen des Wasser- und Elektrolythaushaltes. Klin Wochenschr 51: 361–376

    PubMed  CAS  Google Scholar 

  • Heathfield KWG, Wilhams JRB (1954) Peripheral neuropathy and myopathy associated with bronchial carcinoma. Brain 77: 122–137

    PubMed  CAS  Google Scholar 

  • Henson RA, Russell DS, Wilkinson M (1954) Carcinomatous neuropathy and myopathy: clinical and pathological study. Brain 77: 82–121

    PubMed  CAS  Google Scholar 

  • Heyenga H, Morr H (1982) Diagnostischer Stellenwert des careino-embryonalen Antigens im Pleurapunktat. Dtsch Med Wochenschr 107: 818–821

    PubMed  CAS  Google Scholar 

  • Hirata Y, Matsukura S, Imura H, Nakamura M, Tanaka A (1976) Size heterogeneity of /?-MSH in ectopic ACTH-producing tumors: presence of ß-LPH-like peptide. J Clin Endocrinol Metab 42: 33–40

    PubMed  CAS  Google Scholar 

  • Holling HE, Brodey RS, Boland HC (1961) Pulmonary hypertrophic osteoarthropathy. Lancet 11: 1269–1274

    Google Scholar 

  • Holt GW (1961) Idiopathic neuropathy in cancer. A first sign in multiple system syndromes associated with malignancy. Am J Med Sci 242: 93–106

    PubMed  CAS  Google Scholar 

  • Horai T, Nishihara H, Tateishi R, Matsuda M, Hattorf S (1973) Oat cell carcinoma of the lung simultaneously producing ACTH and serotinin. J Clin Endocrinol 37: 212–219

    CAS  Google Scholar 

  • Huzly A (1973) Einfluß chirurgischer Eingriffe bei Paraneoplasien (I). In: Mlczoch F, Seidel H (Hrsg) Aktuelle Fragen der Lungenpathologie. Lunge und Stoffwechsel, Paraneoplasien, Atemtherapie. Thieme, Stuttgart, S 82–85

    Google Scholar 

  • Imura H (1980) Ectopic hormone syndromes. Clin Endocrinol Metab 9: 235–260

    PubMed  CAS  Google Scholar 

  • Imura H, Nakai Y, Nakao K, Oki S, Matsukura S, Hirata Y, Fukase M, Hattori M, Yoshimi H, Sueoka S (1978) Functioning tumors with special reference to ectopic hormone producing tumors. Prot Nucl Ac Enzyme 23: 641–656

    CAS  Google Scholar 

  • Jones JE, Shane SR, Gilbert E, Flink EF (1969) Cushing’s syndrome induced by the ectopic production of ACTH by a bronchial carcinoid. J Clin Endocrinol Metab 29: 1–5

    PubMed  CAS  Google Scholar 

  • Jonsson M, Houser JM (1956) Scleroderma (progressive systemic sclerosis) associated with cancer of the lung. Brief review and report of a case. N Engl J Med 255: 413–416

    Google Scholar 

  • Kato Y, Ferguson TB, Bennett DE, Burford TH (1969) Oat-cell carcinoma of the lung. A review of 138 cases. Cancer 23: 517–524

    PubMed  CAS  Google Scholar 

  • Kay S, Wilson MA (1970) Ultrastructural studies of an ACTH-secreting thymic tumor. Cancer 26: 445–452

    PubMed  CAS  Google Scholar 

  • Keck E, Göbbeler KH, Peerenboom H, Lilienfeld-Toal von H, Krüskemper HL (1979) Differential- diagnose der Hyperkalzämie durch Messung der renalen Kalziumausscheidung unter Parathormongabe. Dtsch Med Wochenschr 104: 1600–1604

    PubMed  CAS  Google Scholar 

  • Kim HD, Boggs DR (1979) A syndrome resembling idiopathic thrombocytopenic purpura in 10 patients with diverse forms of cancer. Am J Med 67: 371–377

    PubMed  CAS  Google Scholar 

  • Kinloch JD, Webb JM, Eccleston D, Zeitlin J (1965) Carcinoid syndrome associated with oat-cell carcinoma of bronchus. Br Med J 1: 1533

    PubMed  CAS  Google Scholar 

  • Kleist S von, Charanel G, Burtin P (1972) Identification of an antigen from normal human tissue that crossreacts with the carcinoembryonic antigen. Proc Natl Acad Sci USA 69: 2492–2494

    Google Scholar 

  • Kleist S von, King M, Burtin P (1974) Characterization of a normal, tissular antigen extracted from human colonic tumors. Immunoehemistry 11: 249–253

    CAS  Google Scholar 

  • Knight RA, Ratcliffe JG, Besser GM (1971) Tumour ACTH concentrations in ectopic ACTH syndrome and in control tissues. Proc R Soc Med 64: 1266–1267

    PubMed  CAS  Google Scholar 

  • Knowles JH, Smith LH (1960) Extrapulmonary manifestations of bronchogenic carcinoma. N Engl J Med 262: 505–509

    PubMed  CAS  Google Scholar 

  • Kovach R, Kyle LH (1958) Cushing’s syndrome and bronchogenic carcinoma. Am J Med 24: 981–988

    PubMed  CAS  Google Scholar 

  • Krauss St, Macy S, Ichiki AT (1981) A study of immunoreactive calcitonin (CT), adrenocorticotropic hormone (ACTH) and carcinoembryonic antigen ( CEA) in lung cancer and other malignancies. Cancer 47: 2485–2492

    Google Scholar 

  • Kukreja SC, Shemerdiak WP, Lad ThE, Johnson PA (1980) Elevated nephrogenous cyclic AMP with normal serumparathyroid hormone levels in patients with lung cancer. J Clin Endocrinol Metab 51: 167–169

    PubMed  CAS  Google Scholar 

  • Kunkel G (1971) Uber die Bedeutung der venösen Beimischung für die Entstehung von Trommelschlegelfinger und Uhrglasnägel. Pneumonologie 144: 273–278

    PubMed  CAS  Google Scholar 

  • Lafferty FW (1966) Pseudo-hyperparathyroidism. Medicine (Baltimore) 45: 247–260

    CAS  Google Scholar 

  • Lanken N, Fishman AP (1980) Clubbing and hypertrophic osteoarthropathy. In: Fishman AP (ed) Pulmonary diseases and disorders, vol I. McGraw-Hill, New York, p 84

    Google Scholar 

  • Levine RJ, Metz SA (1974) A classification of ectopic hormone-producing tumors. Ann NY Acad Sci 230: 533–546

    PubMed  CAS  Google Scholar 

  • Lewis JM, Searle N, Jordan GL (1960) Cushing’s syndrome and bronchogenic carcinoma. Ann Intern Med 52: 1138–1146

    PubMed  CAS  Google Scholar 

  • Liddle GW, Island DP, Ney RL, Nicholson WE, Shimizu N (1963) Nonpituitary neoplasms and Cushing’s syndrome: Ectopic „adrenocorticotropin“produced by nonpituitary neoplasms as a cause of Cushing’s syndrome. Arch Intern Med 111: 471–475

    Google Scholar 

  • Liddle GW, Nicholson WE, Island DP, Orth DN, Abe K, Lowder StC (1969) Clinical and laboratory studies of ectopic humoral syndromes. Recent Progr Hormone Res 25: 283–314

    PubMed  CAS  Google Scholar 

  • Lipscomb HS, Wilson C, Retienne K, Matsen F, Ward DN (1968) The syndrome of inappropiate secretion of antidiuretic hormone: A case report and characterization of an antidiuret hormonelike material isolated from an oat cell carcinoma of the lung. Cancer Res 28: 378–383

    Google Scholar 

  • Locks MO (1962) Incidence of hypercalcemia in patients with proven lung cancer. Lancet 1 /82: 165–167

    Google Scholar 

  • Lokich JJ (1982) The frequency and clinical biology of the ectopic hormone syndromes of small cell carcinoma. Cancer 50: 2111–2114

    PubMed  CAS  Google Scholar 

  • MacDonald RA, Robbins SL (1957) Significance of nonbacterial thrombotic endocarditis: Autopsy and clinical study of 78 cases. Ann Intern Med 46: 255–273

    PubMed  CAS  Google Scholar 

  • Main RE, Eipper BA, Ling N (1977) Common precursor to corticotropins and endorphins. Proc Natl Acad Sci USA 74: 3014–3018

    Google Scholar 

  • Majcher SJ, Lee ER, Reingold IM, Boyle J, Haverbach BJ (1966) Carcinoid syndrome in bronchogenic carcinoma. Arch Intern Med 117: 57–63

    PubMed  CAS  Google Scholar 

  • Mancall EL, Rosales RK (1964) Necrotizing myelopathy associated with visceral carcinoma. Brain 87: 639 - 656

    PubMed  CAS  Google Scholar 

  • Marks IN, Bank S, Louw JH (1967) Islet cell tumor of the pancreas with reversible watery diarrhea and achlorhydria. Gastroenterology 52: 695–708

    PubMed  CAS  Google Scholar 

  • Matsumoto KK, Peter JB, Schultze RG et al. (1966) Watery diarrhea and hypokalemia associated with pancreatic islet cell adenoma. Gastroenterology 50: 231–242

    Google Scholar 

  • Melmon K, Sjoerdsma A, Mason D (1965) Distinctive clinical and therapeutic aspects of the syndrome associated with bronchial carcinoid tumors. Am J Med 39: 568–585

    PubMed  CAS  Google Scholar 

  • Metz SA, Weintraub B, Rosen SW, Singer J, Robertson RP (1978) Ectopic secretion of chorionic gonadotropin by a lung carcinoma. Am J Med 65: 325–332

    PubMed  CAS  Google Scholar 

  • Milhaud G, Calmette C, Taboulet J, Julienne A, Moukthar MS (1974) Hypersecretion of calcitonin in neoplastic conditions. Lancet 1: 462–463

    PubMed  CAS  Google Scholar 

  • Mlczoch F, Schnetz E (1973) Paraneoplasien. Pathologisch-anatomische Syndrome. In: Mlczoch F, Seidel H (Hrsg) Aktuelle Fragen der Lungenpathologie. Lunge und Stoffwechsel, Paraneoplasien, Atemtherapie. Thieme, Stuttgart, S 58–62

    Google Scholar 

  • Morton, Donald L, Itabashi HH, Grimes DF (1966) Nonmetastatic neurological complications of bronchogenic carcinoma: The carcinomatous neuromyopathies. J Thorac Cardiovasc Surg 51: 14–29

    Google Scholar 

  • Munson PL, Tashjian AH, Levine L (1965) Evidence for parathyroid hormone in non parathyroid tumors associated with hypercalcemia. Cancer Res 25: 1062–1067

    PubMed  CAS  Google Scholar 

  • Nakanishi S, Taii S, Hirata Y, Matsukura S, Imura H, Numa S (1976) A large product of cell-free translation of messenger RNA coding for corticotropin. Proc Natl Acad Sci USA 73: 4319–4323

    PubMed  CAS  Google Scholar 

  • Neville AM, Laurence DJR (1974) Report of the workshop on the carcinoembryonic antigen (CEA): The present position and proposals for future investigations. Int J Cancer 14: 1–18

    Google Scholar 

  • Odell W, Wolfsen AR, Yoshimoto J, Weitzman R, Fisher D, Hirose F (1977) Ectopic peptide synthesis: a universal concomitant of neoplasia. Trans Assoc Am Physicians 90: 204–207

    PubMed  CAS  Google Scholar 

  • Odell W, Wolfsen AR, Bachelot J, Hirose FM (1979) Ectopic production of Lipotropin by cancer. Am J Med 66: 631–638

    PubMed  CAS  Google Scholar 

  • Omenn GS, Roth SI, Baker WH (1969) Hyperparathyroidism associated with malignant tumors of nonparathyroid origin. Cancer 24: 1004–1012

    PubMed  CAS  Google Scholar 

  • Padfield PL, Morton JJ, Brown JJ, Lever AF, Robertson JJ, Wood M, Fox R (1976) Plasma arginine vasopressin in the syndrome of antidiuretic hormone excess associated with bronchogenic carcinoma. Am J Med 61: 825–831

    PubMed  CAS  Google Scholar 

  • Papavasiliou CG (1963) Pulmonary metastases from cancer of the nasopharynx associated with hypertrophic osteoarthropathy. Br J Radiol 36: 680–684

    PubMed  CAS  Google Scholar 

  • Pate JW, Campbell RE, Hughes FA (1960) Unsuspected bronchogenic carcinoma. Dis Chest 37: 56–60

    PubMed  CAS  Google Scholar 

  • Pollard A, Grainger RG, Fleming O, Meachim G (1962) An unusual case of metastasizing bronchial „adenoma“associated with the carcinoid syndrome. Lancet 11: 1084–1086

    Google Scholar 

  • Rassam JW, Anderson G (1975) Incidence of paramalignant disorders in bronchogenic carcinoma. Thorax 30: 86–90

    PubMed  CAS  Google Scholar 

  • Ratcliffe JG, Knight RA, Besser GM, Landon J, Stansfeld AG (1972) Tumour and plasma ACTH concentrations in patients with and without the ectopic ACTH syndrome. Clin Endocrinol (Oxf) 1: 27–44

    CAS  Google Scholar 

  • Rees LH (1975) The biosynthesis of hormones by non-endocrine tumours - A review. J Endocrinol (Oxf) 67: 143–175

    CAS  Google Scholar 

  • Rees LH, Bloomfield GA, Rees GM, Corrin B, Franks LM, Ratcliffe JG (1974) Multiple hormones in a bronchial tumor. J Clin Endocrinol Metab 38: 1090–1097

    PubMed  CAS  Google Scholar 

  • Riggs BL, Sprague RG (1961) Association of Cushing’s syndrome and neoplastic disease, Observations in 232 cases of Cushing’s syndrome and review of literature. Arch Intern Med 108: 841–849

    PubMed  Google Scholar 

  • Riggs BL, Arnaud CD, Reynolds JC, Smith LH (1971) Immunologic differentiation of primary hyperparathyroidism from hyperparathyroidism due to nonparathyroid cancer. J Clin Invest 50: 2079–2082

    PubMed  CAS  Google Scholar 

  • Rimbaut C (1973) L’alpha2 H globuline glyco-proteine reactionelle serique d’origine hepatique, ses rapports avec les affections malignes. Bull Cancer (Paris) 60: 411–420

    Google Scholar 

  • Roof BS, Carpenter B, Fink DJ, Gordan GS (1971) Some thoughts on the nature of ectopic parathyroid hormones. Am J Med 50: 686–691

    PubMed  CAS  Google Scholar 

  • Roos BA, Lindall WA, Baylin SB, O’Neil JA, Freiinger AL, Birnbaum RS, Lambert PW (1980) Plasma immunoreactive calcitonin in lung cancer. J Clin Endocrinol Metab 50: 659–666

    PubMed  CAS  Google Scholar 

  • Rosai J, Higa E (1972) Mediastinal endocrine neoplasm, of probable thymic origin, related to carcinoid tumor. Cancer 29: 1061–1074

    PubMed  CAS  Google Scholar 

  • Rosen SW, Weintraub BD, Vaitukaitis JL, Sussman HH, Hershman JM, Muggia MD (1975) Placental proteins and their subunits as tumor markers. Ann Intern Med 82: 71–83

    Google Scholar 

  • Rosenthal L, Kirsh J (1976) Observations on radionuclide imaging in hypertrophic pulmonary osteoarthropathy. Radiol 120: 359–362

    Google Scholar 

  • Ross EJ (1980) Extrapulmonary syndromes associated with carcinoma of the lung. In: Fishman AP (ed) Pulmonary diseases and disorders, vol II. McGraw-Hill, New York, p 1404

    Google Scholar 

  • Saeed uz Zafar M, Meilinger RC, Fin G, Szabo M, Frohman LA (1979) Acromegaly associated with a bronchial carcinoid tumor: evidence for ectopic production of growth hormone-releasing activity. Clin Endocrinol Metab 48: 66–71

    Google Scholar 

  • Said SJ, Faloona GR (1975) Elevated plasma and tissue levels of vasoactive intestinal polypeptide in the watery-diarrhea syndrome due to pancreatic, bronchogenic and other tumors. N Engl J Med 293: 155 - 160

    PubMed  CAS  Google Scholar 

  • Schein PS, DeLellis RA, Kahn CR, Gordon P, Kraft AR (1973) Islet cell tumors: current concepts and management. Ann Intern Med 79: 239–257

    PubMed  CAS  Google Scholar 

  • Schlipköter HW, Baginski B, Krämer U (1978) Epidemiologische Untersuchungen des Karzinoem- bryonalen Antigens ( CEA) bei Großstadtbewohnern. Zentralbl Bakteriol Mikrobiol Hyg [A] Orig Reihe B 166: 136–143

    Google Scholar 

  • Schlipköter HW, Idel H, Stiller-Winkler R (1982) Immunologische Diagnostik des Bronchialkarzinoms. Prax Klin Pneumol 36: 198–201

    PubMed  Google Scholar 

  • Schmidt-Wermser JG, Nagel GA, Schmid AH (1974) Zur klinischen Diagnose von Hirnmetastasen bei Bronchuscarcinom. Schweiz Med Wochenschr 104: 464–468

    Google Scholar 

  • Schneckloth RE, Mclsaac WM, Page IH (1959) Serotonin metabolism in carcinoid syndrome with metastatic bronchial adenoma. JAMA 170: 1143–1147

    CAS  Google Scholar 

  • Schneider B, Gerwirtz G, Krieger DT, Yalow RS (1973) Big ACTH: conversion to biologically active ACTH by trypsin. Endocrinol [Suppl] 92: A-52

    Google Scholar 

  • Schubert E, Vetter H, Juchems R (1970) Pachydermoperiostosis Tourraine-Solent-Gole-Syndrom. Munch Med Wochenschr 6: 229–235

    Google Scholar 

  • Schürer CC, Peters U, Fischer JTh (1981) Therapeutische Möglichkeiten bei paraneoplastischer Hyperkalzämie. Med Welt 32: 1219–1221

    PubMed  Google Scholar 

  • Schwartz WB, Bennett W, Curelop S, Bartter FC (1957) A syndrome of renal sodium loss and hyponatremia probably resulting from inappropriate secretion of antidiuretic hormone. Am J Med 23: 529–542

    PubMed  CAS  Google Scholar 

  • Semple T, McCluskie RA (1955) Generalized hypertrophic osteoarthropathy in association with bronchial carcinoma. A review based on 24 cases. Br Med J 1: 754–759

    PubMed  CAS  Google Scholar 

  • Senn HJ, Peyer P (1978) Die Therapie des Hyperkalzämie-Syndroms bei Tumorpatienten mit besonderer Berücksichtigung von Mithramycin. Dtsch Med Wochenschr 103: 101–107

    PubMed  CAS  Google Scholar 

  • Seyberth HW, Segre GY, Morgan JL, Sweetman BJ, Potts JT, Oates JA (1975) Prostaglandins as mediators of hypercalcemia associated with certain types of cancer. N Engl J Med 293: 1278–1283

    PubMed  CAS  Google Scholar 

  • Sherwood LM, O’Riordan JL, Aurbach GD, Potts JT (1967) Production of parathyroid hormone by nonparathyroid tumors. J Clin Endocrinol Metab 27: 140–146

    PubMed  CAS  Google Scholar 

  • Silvis SE, Turkbas N, Doscherholmen A (1970) Thrombocytosis in patients with lung cancer. JAMA 211: 1852–1853

    PubMed  CAS  Google Scholar 

  • Skornek AB, Ginsburg LB (1958) Pulmonary hypertrophic osteoarthropathy: Its absence in pulmonary tuberculosis. N Engl J Med 258: 1079

    Google Scholar 

  • Smith RA (1969) Bronchial carcinoid tumours. Thorax 24: 43–50

    PubMed  CAS  Google Scholar 

  • Snedeco PA, Baker HW (1964) Pseudohypoparathyroidism due to malignant tumors. Cancer 14: 1492–1496

    Google Scholar 

  • Sönksen PH, Ayres AB, Braimbridge M, Corrin B, Davies DR, Jeremiah GM, Oaten SW, Lowy C, West TE (1976) Acromegaly caused by pulmonary carcinoid tumours. Clin Endocrinol 5: 503–513

    Google Scholar 

  • Steiner H, Dahlbäck O, Waldenstrom J (1968) Ectopic growth-hormone production and osteoarthropathy in carcinoma of the bronchus. Lancet 1: 783–785

    PubMed  CAS  Google Scholar 

  • Strickland NJ, Bold AM, Medd WE (1967) Bronchial carcinoma with hypercaleaemia simulating cerebral metastases. Br Med J 3: 590–592

    PubMed  CAS  Google Scholar 

  • Strott CA, Nugent CH, Tyler FH (1968) Cushing’s syndrome caused by bronchial adenomas. Am J Med 44: 97–104

    PubMed  CAS  Google Scholar 

  • Sun NCJ, Bowie EJW, Kazmier FJ, Elveback LR, Owen CA (1974) Blood coagulation studies in patients with cancer. Mayo Clin Proc 49: 636–641

    PubMed  CAS  Google Scholar 

  • Taylor DM, Siemsen AW (1965) Bronchogenic carcinoma simulating hyperparathyroidism. Arch Intern Med 115: 67–73

    PubMed  CAS  Google Scholar 

  • Thomas BM (1968) Three unusual carcinoid tumours, with particular reference to osteoblastic bone metastases. Clin Radiol 19: 221–225

    PubMed  CAS  Google Scholar 

  • Thompson GS, Horwich L, Davis JC (1962) Carcinoma of bronchus and Cushing’s syndrome. Lancet II: 534–536

    Google Scholar 

  • Troyer A De, Dramanet J (1975) Correction of antidiuresis by demeclocycline. NJ Engl J Med 293: 915–918

    Google Scholar 

  • Upton GV, Amatruda TT (1971) Evidence for the presence of tumor peptides with corticotropin- releasing factor-like activity in ectopic ACTH syndrome. N Engl J Med 285: 419–424

    PubMed  CAS  Google Scholar 

  • Vaitukaitis JL (1973) Immunological and physical characterization of human chorionic gonadotropin (HCG) secreted by tumours. Clin Endocrinol Metab 37: 505–514

    CAS  Google Scholar 

  • Vassar Ph S, Culling CFA (1962) Nonfunctional bronchial carcinoid tumours. Can Med Assoc J 87: 299–301

    PubMed  CAS  Google Scholar 

  • Verner JV, Morrison AB (1958) Islet cell tumor and a syndrome of refractory watery diarrhea and hypokalemia. Am J Med 25: 374–380

    PubMed  CAS  Google Scholar 

  • Verner JV, Morrison AB (1974) Non-ß islet tumors and the syndrome of watery diarrhea, hypokalemia and hypochlorhydria. Clin Gastroenterol 3: 595–608

    Google Scholar 

  • Videback A (1950) Polycythemia vera: co-existing with malignant tumours (particulary hypernephroma). Acta Med Scand 138: 239–345

    Google Scholar 

  • Vogel MD, Keating FR, Bahn RC (1961) Clinics on endocrine and metabolic disorders. 5. Acute Cushing’s syndrome associated with bronchogenic carcinoma. Mayo Clin Proc 36: 387–393

    Google Scholar 

  • Warner RR, Kirschner PA, Warner GM (1961) Serotonin production by bronchial adenomas without the carcinoid syndrome. JAMA 178: 1175–1179

    PubMed  CAS  Google Scholar 

  • Wegmann D (1981) Paraneoplastische Thrombose - eine mortalitätsstatistische Untersuchung. VASA 10: 111–118

    PubMed  CAS  Google Scholar 

  • Weintraub BD, Rosen SW (1971) Ectopic production of human chorionic somatomammotropin ( HCS) by nontrophoblastic cancer. J Clin Endocrinol Metab 32: 94–101

    Google Scholar 

  • Werk EE Jr, Sholiton LJ, Marnell RT (1963) Further studies of adrenocortical function in patients with carcinoma of the lung. Am J Med 34: 192–212

    PubMed  Google Scholar 

  • West TE, Joffe M, Sinclair L, O’Riordan JL (1971) Treatment of hypercalcaemia with calcitonin. Lancet 1: 675–678

    PubMed  CAS  Google Scholar 

  • Wierman WH, Clagett OT, McDonald JR (1954) Articular manifestations in pulmonary diseases: analysis of their occurrence in 1,024 cases in which pulmonary resection was performed. JAMA 155: 1459–1463

    CAS  Google Scholar 

  • Wilkinson PC (1964) Serological findings in carcinomatous neuromypoathy. Lancet 1: 1301–1303

    PubMed  CAS  Google Scholar 

  • Williams ED, Azzopardi JG (1960) Tumours of the lung and the carcinoid syndrome. Thorax 15: 30–36

    PubMed  CAS  Google Scholar 

  • Williams RC (1959) Dermatomyositis and malignancy: review of literature. Ann Intern Med 50: 1174–1181

    PubMed  Google Scholar 

  • Wolfsen AR, Odell WD (1979) Pro ACTH: Use for early detection of lung cancer. Am J Med 66: 765–772

    Google Scholar 

  • Yacoub MH (1965) Relation between the histology of bronchial carcinoma and hypertrophic pulmonary osteoarthropathy. Thorax 20: 537–539

    Google Scholar 

  • Yalow RS (1974) Heterogeneity of peptide hormones. Recent Prog Horm Res 30: 597–633

    PubMed  CAS  Google Scholar 

  • Yalow RS, Berson SA (1973) Characteristics of big ACTH in human plasma and pituitary extracts. J Clin Endocrinol Metab 36: 415–423

    PubMed  CAS  Google Scholar 

  • Zatuchni J, Campbell WN, Zarafonetis CJ (1953) Pulmonary fibrosis and terminal bronchiolar („alveolar-cell“) carcinoma in scleroderma. Cancer 6: 1147–1158

    PubMed  CAS  Google Scholar 

  • Zawada ET, Lee DB, Kleemann CR (1979) Management of hypercalcemia. Postgrad Med 66: 105–113

    PubMed  Google Scholar 

Download references

Authors
  1. E. Dundalek
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Abteilung für Pneumologie, Medizinische Universitätsklinik und Poliklinik, D-6650, Homburg/Saar, Germany

    M. Austgen

  2. Hangweg 6a, D-6601, Saarbrücken-Schafbrücke, Germany

    H.-W. Beckenkamp (Arbeitsmedizin) (Arbeitsmedizin)

  3. Diagnostiche Abteilung, Krakenhaus Zelendorf, Lungenklinik Heckenshorn, Am Groβen Wannsee 80, D-1000, Berlin 39, Germany

    H.-J. Brandt

  4. Innere Abteilung, Zentralkrankenhaus, Unterbrunner Str. 85, D-8035, Gauting, Germany

    U. Dold

  5. Zentralklinik für Herz-und Lungenkrankheiten, Röntgenstr. 2, DDR-5302, Bad Berka, Germany

    H. Dürschmied

  6. Krakenhaus Merheim, Medizinische Klinik, Ostmerheimer Str. 200, D-5000, Köln 91, Germany

    E. Dundalek

  7. Strahlenklinik und Poliklinik (WE 07), Abteilung Radiologie, Univesitätsklinikum Charlottenburg, Spandauer Damm 130, D-1000, Berlin 19, Germany

    R. Felix

  8. Zentrum Radiologie (Strahlenklinik), Abteilung Nuklearmedizin, Klinikum der Univesität, Voβstr. 3, D-6900, Heidelberg 1, Germany

    P. Georgi

  9. Karl-Marx-Str. 9, DDR-1615, Zeuthen bei, Berlin, Germany

    H.-J. Herold

  10. Abteilung Experimentelle Tumorforschung, Asta-Werke, Degussa Pharma Gruppe, Artur-Ladebeck-Str. 128–152, D-4800, Bielefeld 14, Germany

    P. Hilgard

  11. Abteilung für Arbeits-und Sozialhygiene und Gesundheitsplanung, Klinikum der Universität, Im Neuenheimer Feld 368, D-6900, Heidelberg, Germany

    W. Jacob

  12. Medizinische Universitätsklinik I, Joseph-Stelzmann-Str. 9, D-5000, Köln 41, Germany

    H. O. Klein

  13. Abteilung für Innere Medizin und Funktionsdiagnostik, Ruhrlandklinik, Tüschener Weg 40, D-4300, Essen 16, Germany

    N. Konietzko

  14. Innere Abteilung, Krankenhaus Zehlendorf, Lungenklinik Heckeshorn, Am Groβen Wannsee 80, D-1000, Berlin 39, Germany

    R. Loddenkemper

  15. Ruhrlandklinik, Tüschener Weg 40, D-4300, Essen 16, Germany

    W. Maaßen

  16. Radiologische Abteilung, Univesität Gifu, Tsukasa-Machi 40, 500, Gifu, Japan

    E. Matsui

  17. Innere Abteilung, Krankenhaus Zehlendorf, Lungenklinik Heckeshorn, Am Groβen Wannsee 80, D-1000, Berlin 39, Germany

    W. Matthiessen

  18. Radilogisches Zentralinstitut, Krankenhaus Siegburg GmbH., Ringstr. 49, D-5200, Siegburg, Germany

    H. Meents

  19. Institut für Pathologie, Berufsgenossenschaftliche Krankenanstalten „Bergmannsheil Bochum“, Universitätsklinik, Hunscheidtstr. 1, D-4630, Bochum 1, Germany

    K.-M. Müller

  20. Institut für Nuklearmedizin, Deutsches Krebsforschugszentrum, Im Neuenheimer Feld 280, D-6900, Heidelberg 1, Germany

    H. Ostertag

  21. Abteilung für Pneumonologie, Medizinische Universitätsklinik und Poliklinik, D-6650, Homburg, Saar, Germany

    P. Schlimmer

  22. Institut für Toxikologie und Chemotherapie, Deutsches Krebsforschugszentrum, Im Neuenheimer Feld 280, D-6900, Heidelberg 1, Germany

    D. Schmähl

  23. Radiologisches Zentralinstitut, Krankenhaus Siegburg GmbH., Ringstr. 49, D-5200, Siegburg, Germany

    R. Schober

  24. Allgemeines Krankenhaus Altona, Paul-Ehrlich-Str. 1, D-2000, Hamburg 50, Germany

    O. H. Wegener

  25. Winzerstr. 9, D-7800, Freiburg i.Br., Germany

    W. Wolfart

  26. Institut für Toxikologie und Chemotherapie, Deutsches Krebsforschugszentrum, Im Neuenheimer Feld 280, D-6900, Heidelberg 1, Germany

    W. J. Zeller

  27. Abteilung für Pneumonologie, Medizinische Univesitätsklinik und Poliklinik, D-6650, Homburg, Saar, Germany

    Friedrich Trendelenburg

Rights and permissions

Reprints and permissions

Copyright information

© 1985 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Dundalek, E. (1985). Paraneoplasien der Neoplasmen der Bronchien und der Lunge. In: Austgen, M., et al. Tumoren der Atmungsorgane und des Mediastinums A. Handbuch der inneren Medizin, vol 4 / 4 / A. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70147-4_7

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-70147-4_7

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-70148-1

  • Online ISBN: 978-3-642-70147-4

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation