Somatosensory Evoked Potential (SEP) in Myoclonus
History of somatosensory evoked potential (SEP) in humans starts from Dawson’s finding of an extremely large EEG response to peripheral nerve stimulation in patients with myoclonic epilepsy (1). This giant SEP was shown to be characteristic of “pyramidal” myoclonus by Halliday (4) and of “cortical reflex” myoclonus by Hallett et al. (3). Physiological mechanisms of the giant SEP have not been elucidated. In this paper, therefore, diagnostic usefulness of SEP and physiological significance of the giant SEP will be reported.
KeywordsCortical Excitability Somatosensory Evoke Potential Myoclonic Epilepsy Peripheral Nerve Stimulation Thenar Muscle
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