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Electromyography and Evoked Potentials pp 2–8Cite as

Animal Models of Motor Disorders

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Part of the book series: Advances in Applied Neurological Sciences ((NEUROLOGICAL,volume 1))

Abstract

It would obviously be of great value to have reliable animal models of neurological motor disorders in man to assess therapeutic procedures in preclinical evaluations and also to learn more about pathophysiological mechanisms. In this brief review, I wish to concentrate on the problem of increased muscle tone which, as a “positive” symptom in many neurological disorders, is therapeutically more accessible than are “negative” symptoms such as muscle weakness. Thus, I will deal with the question how spasticity occurring in the presence of spinal and supraspinal lesions and rigidity associated with basal ganglia disorders, may be studied in animal experiments.

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Author information

Authors and Affiliations

  1. Institut de Physiologie, Université de Fribourg, CH-1700, Fribourg, Switzerland

    M. Wiesendanger

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  1. M. Wiesendanger
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Editor information

Editors and Affiliations

  1. Neurologische Klinik und Poliklinik, Technischen Universität München, Möhlstraße 28, D-8000, München 80, Germany

    Albrecht Struppler  & Adolf Weindl  & 

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© 1985 Springer-Verlag Berlin Heidelberg

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Wiesendanger, M. (1985). Animal Models of Motor Disorders. In: Struppler, A., Weindl, A. (eds) Electromyography and Evoked Potentials. Advances in Applied Neurological Sciences, vol 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70122-1_1

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  • DOI: https://doi.org/10.1007/978-3-642-70122-1_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-70124-5

  • Online ISBN: 978-3-642-70122-1

  • eBook Packages: Springer Book Archive

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