Skip to main content

Clinical Aspects of Adult T-Cell Leukemia/Lymphoma

  • Chapter
Human T-Cell Leukemia Virus

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 115))

Abstract

Since adult T-cell leukemia (ATL) was first proposed as a new disease by Takatsuki and associates (Takatsuki etal. 1977; Uchiyama etal. 1977) in Kyoto, we estimate that more than 500 patients with ATL have been detected so far in Japan. Most of them are from Kyushu, the southernmost island of Japan, although the disease is also endemic in southern Shikoku and some parts of Honshu, including Sadogashima, an island near Niigata, and Ishinomaki, an area on the north of Sendai.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Blattner WA, Kalyanaraman VS, Robert-Guroff M, Lister TA, Galton DAG, Sarin PS, Crawford MH, Catovsky D, Greaves M, Gallo RC (1982) The human type-c retrovirus, HTLV, in blacks from the Caribbean region, and relationship to adult T-cell leukemia/lymphoma. Int J Cancer 30: 257–264

    Article  PubMed  CAS  Google Scholar 

  • Hinuma Y, Nagata K, Hanaoka M, Nakai M, Matsumoto T, Kinoshita K, Shirakawa S, Miyoshi I (1981) Antigen in an adult T-cell leukemia cells line and detection of antibodies to the antigen in human sera. Proc Natl Acad Sei USA 78: 6476–6480

    Article  CAS  Google Scholar 

  • Ichimaru M, Kinoshita K, Kamihira S, Yamada Y, Oyakawa Y, Amagasaki T, Kusano M (1982) Familial disposition of adult T-cell leukemia and lymphoma. In: Hanaoka M, Takatsuki K, Shimoyama M (eds) Adult T-cell leukemia and related diseases. Japan Scientific Societies, Tokyo, pp 185–195 (Monographs on Cancer Research, 28 )

    Google Scholar 

  • Kawano F, Tsuda H, Yamaguchi K, Nishimura Hl, Sanada I, Matsuzaki H, Ishii M, Takatsuki K (1984) Unusual clinical courses of adult T-cell leukemia in siblings. Cancer (in press)

    Google Scholar 

  • Miyamoto Y, Yamaguchi K, Nishimura H, Takatsuki K, Motoori T, Morimatsu M, Yasaka T, Ohya I, Koga T (1984) Familial adult T-cell leukemia. Cancer 54: 131–134

    Article  Google Scholar 

  • Miyoshi I, Kubonishi I, Sumida M, Hiraki S, Tsubota T, Kimura I, Miyamoto K, Sato J (1980) A novel T-cell line derived from adult T-cell leukemia. Gann 71: 155–156

    PubMed  CAS  Google Scholar 

  • Poiesz BJ, Ruscetti FW, Fazdar AF, Bunn PA, Minna JD, Gallo RC (1980) Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma. Proc Natl Acad Sei USA 77: 7415–7419

    Article  CAS  Google Scholar 

  • Seiki M, Hattori S, Hirayama Y, Yoshida M (1983) Human adult T-cell leukemia virus: Complete nucleotide sequence of the pro virus genome integrated in leukemia cell DNA. Proc Natl Acad Sei USA 80: 3618–3622

    Article  CAS  Google Scholar 

  • Southern EM (1975) Detection of specific sequences among DNA fragments separated by gel electro phoresis. J Mol Biol 98: 503–517

    Article  PubMed  CAS  Google Scholar 

  • Suchi T, Tajima K, Nanba K, Wakasa H, Mikasa A, Kikuchi M, Mori S, Watanabe S, Mohri N, Shamoto M, Harigaya K, Itagaki T, Matsuda M, Kirino Y, Takagi K, Fukunaga S (1979) Some problems on the histopathological diagnosis of non-Hodgkin’s malignant lymphoma-pro posal of a new type. Acta Pathol Jpn 29: 755–776

    PubMed  CAS  Google Scholar 

  • Tajima K, Tominaga S, Kuroishi T, Shimizu H, Suchi T (1979) Geographical features and epidemiological approach to endemic T-cell leukemia/lymphoma in Japan. Jpn J Clin Oncol 9(suppl):459–504

    Google Scholar 

  • Takatsuki K, Uchiyama T, Sagawa K, Yodoi J (1977) Adult T cell leukemia in Japan. In: Seno S, Takaku F, Irino (eds) Topics in hematology. Excerpta Medica, Amsterdam, pp 73–77

    Google Scholar 

  • Takatsuki K, Uchiyama T, Ueshima Y, Hattori T, Toibana T, Tsudo M, Wano Y, Yodoi J (1982) Adult T cell leukemia: Proposal as a new disease and cytogenetic, phenotypic, and functional studies of leukemic cells. In: Hanaoka M, Takatsuki K, Shimoyama M (eds) Adult T-cell leukemia and related diseases. Japan Scientific Societies, Tokyo, pp 13–22 (Gann Monograph on Cancer Research, 28 )

    Google Scholar 

  • Uchiyama T, Yodoi J, Sagawa K, Takatsuki K, Uchino H (1977) Adult T cell leukemia. Clinical and hematologic features of 16 cases. Blood 50: 481–492

    PubMed  CAS  Google Scholar 

  • Yamaguchi K, Nishimura H, Kohrogi H, Jono M, Miyamoto Y, Takatsuki K (1983) A proposal for smoldering T-cell leukemia (smoldering ATL): A clinicopathologic study of 5 cases. Blood 62: 758–766

    PubMed  CAS  Google Scholar 

  • Yamaguchi K, Nishimura H, Kawano F, Kohrogi H, Jono M, Miyamoto Y, Takatsuki K (1983) A proposal for smoldering adult T-cell leukemia-Diversity in clinical pictures of adult T-cell leukemia. Jpn J Clin Oncol 13 (suppl 2):189–200

    PubMed  Google Scholar 

  • Yamaguchi K, Seiki M, Yoshida M, Nishimura H, Kawano F, Takatsuki K (1984) The detection of human T-cell leukemia virus proviral DNA and its application for Classification and diagnosis of T-cell malignancy. Blood63: 1235–1240

    PubMed  CAS  Google Scholar 

  • Yoshida M, Miyoshi I, Hinuma T (1982) Isolation and characterization of retrovirus from cell lines of human adult T-cell leukemia and its implication in the disease. Proc Natl Acad Sei USA79: 2031–2035

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1985 Springer-Verlag Berlin · Heidelberg

About this chapter

Cite this chapter

Takatsuki, K., Yamaguchi, K., Kawano, F., Nishimura, H., Seiki, M., Yoshida, M. (1985). Clinical Aspects of Adult T-Cell Leukemia/Lymphoma. In: Vogt, P.K. (eds) Human T-Cell Leukemia Virus. Current Topics in Microbiology and Immunology, vol 115. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70113-9_6

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-70113-9_6

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-70115-3

  • Online ISBN: 978-3-642-70113-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics