Primary Structure and Processing of gag and env Gene Products of Human T-Cell Leukemia Viruses HTLV-ICR and HTLV-IATK

  • Stephen Oroszlan
  • Terry D. Copeland
Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 115)


Many of the immunological and biochemical properties of HTLV internal and envelope proteins are discussed in other chapters of this volume. Here we summarize the results of our published and ongoing studies on the primary structure of human T-0cell leukemia virus (HTLV) gag and env gene products. In addition to the previously known structural proteins p19, p24, p15, and gp46, the use of antibodies to synthetic peptides enabled us to characterize partially the transmembrane protein p21env and a low molecular weight glycoprotein gp16, which have not been identified previously.


Bovine Leukemia Virus Complete Amino Acid Sequence Nucleic Acid Binding Protein Complete Primary Structure Primary Structure Analysis 
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Copyright information

© Springer-Verlag Berlin · Heidelberg 1985

Authors and Affiliations

  • Stephen Oroszlan
    • 1
  • Terry D. Copeland
    • 1
  1. 1.Laboratory of Molecular Virology and Carcinogenesis, LBI-Basic Research ProgramNCI-Frederick Cancer Research FacilityFrederickUSA

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