Molecular Biology of Human T-Cell Leukemia Virus Associated with Adult T-Cell Leukemia

  • Mitsuaki Yoshida
  • Seisuke Hattori
  • Motoharu Seiki
Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 115)

Abstract

Many retroviruses have been isolated from various species of animals and these have provided useful systems for studying the mechanisms of tumorigenesis; a number of viral onc genes and the corresponding cellular proto-onc genes that have been conserved during evolution have been identified (Vogt 1977; Bishop 1982). From the studies of these viruses and protoonc genes, general mechanisms of tumorigenesis have been proposed (Hayward et al. 1981; Weinberg 1982). Based on these recent developments, it now seems likely that human retroviruses will provide helpful information for molecular analysis of cellular transformation in the human system. However, until recently, human retroviruses were not well characterized, although many preliminary observations have been reported.

Keywords

Sucrose Lymphoma Codon Leukemia Electrophoresis 

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Copyright information

© Springer-Verlag Berlin · Heidelberg 1985

Authors and Affiliations

  • Mitsuaki Yoshida
    • 1
  • Seisuke Hattori
    • 1
  • Motoharu Seiki
    • 1
  1. 1.Department of Viral OncologyCancer InstituteKami-Ikebukuro, Toshima-ku, TokyoJapan

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