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DNA Cytophotometry

  • Wolfgang Leistenschneider
  • Reinhard Nagel

Abstract

Whereas cytomorphological examination of cells and nuclei permits qualitative assessment of prostatic disease only, cytophotometry allows quantitative assessment of the biological behavior, i.e. the malignancy potential, of the prostatic carcinoma before and during treatment with all known forms of therapy, by means of detailed analysis of the nuclear DNA. Cell kinetics can also only be determined by quantitative measurement of the nuclear DNA content, i.e. by cytophotometry and not by autoradiography or liquid scintillation spectrophotometry, which are methods of measuring DNA synthesis by incorporating radioactive-labelled thymidine (H3).

Keywords

Free Aldehyde Group Potassium Metabisulfite Photometer Microscope Median Quartile Methanol Alcohol 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1985

Authors and Affiliations

  • Wolfgang Leistenschneider
    • 1
  • Reinhard Nagel
    • 1
  1. 1.Urologische Klinik und Poliklinik, Klinikum CharlottenburgFreien Universität BerlinBerlin 19Germany

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