Whereas cytomorphological examination of cells and nuclei permits qualitative assessment of prostatic disease only, cytophotometry allows quantitative assessment of the biological behavior, i.e. the malignancy potential, of the prostatic carcinoma before and during treatment with all known forms of therapy, by means of detailed analysis of the nuclear DNA. Cell kinetics can also only be determined by quantitative measurement of the nuclear DNA content, i.e. by cytophotometry and not by autoradiography or liquid scintillation spectrophotometry, which are methods of measuring DNA synthesis by incorporating radioactive-labelled thymidine (H3).
KeywordsFormalin Hydrolysis Adenoma Lysine Arginine
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