Role of Calcium in Alpha-Adrenergic Regulation of Liver Function

  • J. H. Exton


The liver can be affected by the sympathetic nervous system via epinephrine and norepinephrine released into the bloodstream from the adrenal medulla or via norepinephrine released from adrenergic nerve endings within the liver. As is the case for other tissues of the body, the receptors to these catecholamines are of two major types designated α- and β-adrenergic receptors. The liver α-receptors are mainly of the α l -subtype (Hoffman et al. 1979,1981) and the liver β-receptors are mainly of the β 2 -subtype (Morgan et al. 1983).


Glycogen Phosphorylase Liver Plasma Membrane Inositol Trisphosphate Hepatic Glucose Output Phosphorylase Activation 
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Copyright information

© Springer-Verlag, Berlin Heidelberg 1985

Authors and Affiliations

  • J. H. Exton
    • 1
  1. 1.Laboratories for the Studies of Metabolic Disorders, Howard Hughes Medical Institute and Department of PhysiologyVanderbilt University School of MedicineNashvilleUSA

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