The Role of Calcium in Prostaglandin and Thromboxane Biosynthesis
Prostaglandins and thromboxanes are biologically potent compounds derived from arachidonic acid. They are synthesized in a wide variety of tissues in response to various stimuli, and are known to modulate numerous physiological processes. These compounds are not stored within the cell, and their effects are restricted to the cell in which they are synthesized or to neighboring cells. Their precise mechanisms of action are not well understood; in general, their actions are believed to be mediated via cyclic AMP, or Ca2+.
KeywordsCholine Thrombin Indomethacin Hydroperoxide Inositol
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