The Role of Calcium in Prostaglandin and Thromboxane Biosynthesis

  • L. R. Ballou
  • W. Y. Cheung


Prostaglandins and thromboxanes are biologically potent compounds derived from arachidonic acid. They are synthesized in a wide variety of tissues in response to various stimuli, and are known to modulate numerous physiological processes. These compounds are not stored within the cell, and their effects are restricted to the cell in which they are synthesized or to neighboring cells. Their precise mechanisms of action are not well understood; in general, their actions are believed to be mediated via cyclic AMP, or Ca2+.


Arachidonic Acid Human Platelet Phosphatidic Acid Arachidonic Acid Release Arachidonate Release 
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Copyright information

© Springer-Verlag, Berlin Heidelberg 1985

Authors and Affiliations

  • L. R. Ballou
  • W. Y. Cheung
    • 1
  1. 1.Departments of BiochemistrySt. Jude Children’s Research Hospital and The University of Tennessee Center for the Health SciencesMemphisUSA

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