Summary
The possibility of controlling terrestrial wild-life rabies by immunization rather than by population reduction has been under active consideration for the last 15–20 years. The idea is to provide vaccine in bait which is readily acceptable to the species concerned — for example, the fox in Western Europe and parts of North America.
Attention has been largely focussed on the idea of using live attenuated vaccines in the bait and recently highly successful field trials conducted in Switzerland have shown that the advance of the disease may be halted in this way.
However, none of the live vaccines at present available appears to be completely safe for all species and it is generally accepted that very strict measures of control must be applied if this procedure is extended.
We present results which suggest that it may be possible to use inactivated vaccines for the control of wild life rabies and thus avoid any risk associated with the widespread dispersal of live virus.
Résumé
Pendant les dernières 15–20 années, la possibilité de lutter contre la rage selvatique terrestre par la vaccination plutôt que par une réduction de la population animale a été fortement discutée. Le projet a pour but d’offrir aux animaux susceptibles des appâts contenant du vaccin — appâts qu’ils accepteraient volontairement — par exemple, aux renards en Europe Occidentale et dans certaines régions de l’Amérique du Nord.
L’attention a été surtout attirée à l’idée d’introduire dans l’appât des vaccins vivants atténués. Des essais récents sur le terrain en Suisse ont remporté du succès et indiquent que la distribution de la maladie puisse être arrêtée de cette façon.
Cependant, parmi des vaccins vivants actuellement disponibles, aucun ne parait complètement sans risques à toutes les espèces. Il est donc généralement accepté que des très fortes mesures de lutte doivent être adoptées si cette méthode est poussée plus loin.
Nous présentons des résultats qui indiquent la possibilité d’employer des vaccins inactivés pour lutter contre la rage selvatique. Ceux-ci éviteraient donc le risque considérable associé à la distribution sur une grande étendue de virus vivant.
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Crick, J., Brown, F., King, A.A., Williams, E.W., Thompson, G., Fearne, A.J. (1985). Control of Wildlife Rabies. In: Kuwert, E., Mérieux, C., Koprowski, H., Bögel, K. (eds) Rabies in the Tropics. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70060-6_39
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DOI: https://doi.org/10.1007/978-3-642-70060-6_39
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