Summary
Despite increasing efforts to eliminate human and animal rabies, the WHO reports that hundreds of thousands of individuals throughout the world, including a large number of children, receive antirabies treatment each year.
Between 1975 and 1981, 921 persons bitten by a domestic or wild animal were given rabies post-exposure treatment on days 0, 3, 7, 14, 30, 90 at the Reims antirabies Center, including 289 children under 15 years of age. 8 of them were under one year and 166 between 2 and 10 years. In 26% of cases, animal rabies was confirmed by the laboratory.
The results of this study, demonstrated the perfect tolerance and perfect clinical and serological effectiveness of the human diploid cell vaccine.
Résumé
Malgré les mesures associant de plus en plus souvent la lutte contre la rage humaine et animale, l’O.M.S. signale que des milliers de personnes, dont un grand nombre d’enfants, font, chaque année dans le monde, l’objet de traitements antirabiques.
Au centre antirabique de Reims, entre 1975 et 1981, 921 personnes mordues, par un animal domestique ou sauvage suspect de rage, dont 289 enfants âgés de moins de 15 ans — 8 de moins d’un an et 166 entre 2 et 10 ans — ont eu un traitement antirabique en post-exposition aux jours J0, J3, J7, J14, J30 et J90. Dans 26% des cas, la preuve de rage animale a été confirmée au laboratorie.
Les résultats de cette étude ont montré la parfaite tolérance ainsi que la parfaite efficacité clinique et sérologique du vaccin cultivé sur cellules diploīdes humaines.
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© 1985 Springer-Verlag Berlin, Heidelberg
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Ajjan, N., Strady, A., Roumiantzeff, M., Xueref, C. (1985). Effectiveness and Tolerance of Rabies Post-Exposure Treatment with Human Diploid Cell Rabies Vaccine in Children. In: Kuwert, E., Mérieux, C., Koprowski, H., Bögel, K. (eds) Rabies in the Tropics. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70060-6_11
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DOI: https://doi.org/10.1007/978-3-642-70060-6_11
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