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Correlation Between CBF and pCO2, pO2, pH, Hemoglobin, Blood Pressure, Age, and Sex

  • P. Gündling
  • J. Haneder
  • M. R. Gaab

Abstract

While many investigations concerning the influence of certain parameters on the CBF, like carbon dioxide pressure (pCO2) and hemoglobin, have been carried out, such parameters as age and sex have not normally been taken into account. Therefore the existing correcting formulas seem to be too restrictive and, besides this, too inflexible. This means that they are valid for every cerebral disorder and depend on the absolute CBF values (higher values are corrected more than lower ones; a better formula should do the opposite. Thus the questions leading us to our study have been:
  1. 1.

    Which parameters do influence the cerebral blood flow in various groups?

     
  2. 2.

    Are these influences similar in various kinds of cerebral disorder?

     
  3. 3.

    Are the existing correcting formulas adequate?

     
  4. 4.

    If not, is it possible to find a formula to eliminate all these influences in order to obtain standardized results to enable, for example, a comparison of different methods of medical treatment?

     

Keywords

Ischemic Stroke Cerebral Blood Flow Transient Ischemic Attack Regional Cerebral Blood Flow Cerebral Atrophy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Deshmukh VD, Meyer JS (1978) Noninvasive measurement of regional cerebral blood flow in man. SP Medical and Scientific Books, New York, London, p 129–151Google Scholar
  2. Herrschaft HF (1975) Die regionale Gehirndurchblutung. Springer, Berlin, Heidelberg, New YorkGoogle Scholar
  3. Obrist WD et al. (1967) Determination of regional cerebral blood flow by inhalation of 133-xenon. Circulation Research, Vol. XX, p 124–135Google Scholar
  4. Olesen J (1974) Cerebral blood flow methods for measurement regulation, effects of drugs and changes in disease. Fadl, Kobenhaven, Arhus, Odense, p 11–18Google Scholar
  5. Risberg J et al. (1975) Stroke 6, p 142–148PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1985

Authors and Affiliations

  • P. Gündling
    • 1
  • J. Haneder
    • 1
  • M. R. Gaab
    • 1
  1. 1.Neurochirurgische Universitätsklinik, KopfklinikWürzburgGermany

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