Methodological Problems in the Clinical Application of the Atraumatic Xenon Techniques
The purpose of this paper is to outline some of the problems in the clinical application of the noninvasive xenon 133 inhalation and intravenous injection methods of cerebral blood flow measurement, and any subsequent mention of methodology refers to these two techniques. There are a number of pitfalls for the unwary in the clinical use of these methods, and these can be divided into two main groups. Firstly, the inappropriate use of equipment and overinterpretation of data and, secondly, possible errors due to assumptions made in the method itself.
KeywordsSubtraction Technique Clearance Curve Cerebral Blood Flow Measurement Inhalation Time Arteriovenous Oxygen Difference
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