Abstract
Several factors have been identified as reducing cerebral blood flow (CBF) following cerebral infarction, among which the role of blood viscosity has attracted increasing interest during the past few years. An increase of whole blood viscosity may be produced by several factors, such as high hematocrit (hct), enhanced aggregation of platelets (PAG) and of red cells (RCA), loss of red cell elasticity (RCE), and an increase of the fibrinogen content. Likewise, a close correlation between whole blood viscosity and CBF has been established in normals as well as in cerebrovascular disease (CVD).
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References
Breddin K, Grun H, Krzywanek H et al. (1975) Zur Messung der spontanen Thrombocytenaggregation. Klin. Wschr. 53: 81–89
Grotta J, Ackermann R, Correia J et al. (1982) Whole blood viscosity parameters and cerebral blood flow. Stroke 13: 296–301
Obrist WD, Thompson HD, Wang HS et al. (1975) Regional cerebral blood flow estimated by 133 xenon inhalation. Stroke 6: 245–256
Ott E, Lechner H (1982) Haemorheologic and haemodynamic aspects of cerebrovascular disease. Path Biol 30: 611–614
Ott E, Lechner H, Aranibar A (1974) High blood viscosity syndrome in cerebral infarction. Stroke 5: 330–333
Ott E, Ladurner G, Lechner H (1977) Relationship between disturbed rheological properties and cerebral haemodynamics in recent cerebral infarction. Progr Biochem 14: 349–352
Ott E, Lechner H, Aranibar A et al. (1979) Impairment of rheologic conditions and cerebral blood flow in patients with cerebral vascular disease. In: Cerebral vascular disease 2. Meyer JS, Lechner H, Reivich M (eds) Excerpta Medica, Amsterdam
Reid HC, Barnes AJ, Dormandy TC (1976) A simple method for measuring erythrocyte de- formability. Clin Path 29: 855–858
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This paper is dedicated to Prof. Dr. H. Schurz, Chairman of the Institute for Physical Chemistry, University of Graz, on the occasion of his 60th birthday
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© 1985 Springer-Verlag Berlin Heidelberg
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Ott, E., Fazekas, F., Bertha, G., Valetitsch, H., Lechner, H. (1985). Rheological Determinants of Cerebral Blood Flow. In: Hartmann, A., Hoyer, S. (eds) Cerebral Blood Flow and Metabolism Measurement. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70054-5_18
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DOI: https://doi.org/10.1007/978-3-642-70054-5_18
Publisher Name: Springer, Berlin, Heidelberg
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