Rheological Determinants of Cerebral Blood Flow
Several factors have been identified as reducing cerebral blood flow (CBF) following cerebral infarction, among which the role of blood viscosity has attracted increasing interest during the past few years. An increase of whole blood viscosity may be produced by several factors, such as high hematocrit (hct), enhanced aggregation of platelets (PAG) and of red cells (RCA), loss of red cell elasticity (RCE), and an increase of the fibrinogen content. Likewise, a close correlation between whole blood viscosity and CBF has been established in normals as well as in cerebrovascular disease (CVD).
KeywordsFiltration Fibrinogen Xenon Polycythemia
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