Methods for the Study of Cyclic Nucleotides in the Nervous System of Insects

  • P. F. T. Vaughan
Part of the Springer Series in Experimental Entomology book series (SSEXP)


Evidence has accumulated during the past 15 years, which suggests that the cyclic nucleotides (cyclic-3′,5′-adenosine monophosphate, cAMP and cyclic-3′,5′-guanosine monophosphate, cGMP) may function as second messengers in mediating the effects of some neurotransmitters (Beam and Greengard 1975; Greengard 1976; Kupfermann 1980). A good example of a situation in which cAMP acts as a second messenger in the CNS is provided by the mammalian cerebellar cortex (Kupfermann 1980), for which it has been established that the slow inhibitory effect of noradrenaline on Purkinje cells is mediated by cAMP (Bloom 1975).


Adenylate Cyclase Cyclic Nucleotide Nerve Cord Cerebral Ganglion Phosphodiesterase Activity 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1985

Authors and Affiliations

  • P. F. T. Vaughan
    • 1
  1. 1.Glasgow UniversityGlasgowScotland

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