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Isolation and Characterization of Neuropeptides

  • M. H. Schaffer
Part of the Springer Series in Experimental Entomology book series (SSEXP)

Abstract

The recognition of neuropeptides as a major class of neurotransmitters has led to a set of revolutionary discoveries about chemical neurotransmission. Widely held ideas about the total number of neurotransmitters, the number of transmitters used by a single neuron, the anatomical structures over which transmitters act, and the array of postsynaptic events they produce have changed in the last 5 to 10 years, and in large measure studies of neuropeptides are responsible for those changes. Thus, it seems clear that neuropeptides are a class of neurotransmitters well worth studying, not only because of their inherent significance to the physiology of the nervous system, but also because modern tools available for the study of neuropeptides make them excellent models for the study of neurotransmission in general.

Keywords

Amino Acid Analysis Fast Atom Bombardment Edman Degradation Dansyl Chloride Picomole Range 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Abbreviations

Abbreviations

AKH

adipokinetic hormone

c.c

corpora cardiac

cDNA

complementary DNA

DABS

4-dimethylaminoazobenzene-4′-sulfonyl

ELH

egg-laying hormone

FAB

fast atom bombardment

GPC

gel permeation chromatography

HPLC

high performance liquid chromatography

MS

mass spectrometry

pGlu

pyroglutamate

PTHaa

phenylthiohydantoin-amino acid

Symbols

Å

angstrom

mM

millimolar

µ

micron

nm

nanometer

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Copyright information

© Springer-Verlag Berlin Heidelberg 1985

Authors and Affiliations

  • M. H. Schaffer
    • 1
  1. 1.University of ChicagoChicagoUSA

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