Skip to main content
Book cover

Neurology pp 282–287Cite as

Epidemiology of Multiple Sclerosis

  • Conference paper

Abstract

The most important facts and views emerging from the observations described in surveys of the epidemiology of multiple sclerosis (MS) may be grouped as follows.

  1. 1.

    Geographic distribution and clustering

  2. 2.

    Migration and geographic isolation

  3. 3.

    Genetics, immunogenetics, and environmental factors

  4. 4.

    Comparative clinicopathology and special features

  5. 5.

    Source of data and diagnosis

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Alter M, Halpern L, Kurland LT, Bornstein D, Leibowitz U, Silberstein J (1962) Multiple sclerosis in Israel. Prevalence among immigrants and native inhabitants. Arch Neurol 7: 15–25

    Google Scholar 

  2. Alter M, Kahana E, Loewenson R (1978) Migration and risk of multiple sclerosis. Neurology 28: 1089–1093

    PubMed  CAS  Google Scholar 

  3. Antonowsky A, Leibowitz U, Medalie JM, Smith HA, Halpern L, Alter M (1967) Epidemiological study of multiple sclerosis in Israel, part 3. Multiple sclerosis and socioeconomic status. J Neurol Neurosurg Psychiatry 30: 1–6

    Article  Google Scholar 

  4. Bauer HJ (1980) IMAB-Enquete concerning the diagnostic criteria for MS. In: Bauer HJ, Poser S, Ritter G (eds) Progress in multiple sclerosis research. Springer, Berlin Heidelberg New York, pp 555–563

    Google Scholar 

  5. Bejar JM, Ziegler DK (1984) Onset of multiple sclerosis in a 24-month-old child. Arch Neurol 41: 881–882

    PubMed  CAS  Google Scholar 

  6. Berman M, Feldman S, Alter M et al. (1981) Acute transverse myelitis incidence and etiologic considerations. Neurology 31: 966–971

    PubMed  CAS  Google Scholar 

  7. Brandt S, Gyldensted C, Offner H, Melchior JL (1981) Multiple sclerosis in a two-year-old boy. Neuropediatries 12: 75–82

    Article  CAS  Google Scholar 

  8. Cendrowski W, Wender M, Dominik W, Fleisierowicz, Owsianowski M, Popiel M (1969) Epidemiological study of multiple sclerosis in Western Poland. Eur Neurol 2: 90–100

    Article  PubMed  CAS  Google Scholar 

  9. Dean G (1967) Annual incidence, prevalence and mortality of multiple sclerosis in white South-African born and in white immigrants to South Africa. Br Med J 2: 724–730

    Article  PubMed  CAS  Google Scholar 

  10. Dean G (1982) Multiple sclerosis among Asian immigrants to England and multiple sclerosis in southern Europe-Sicily and Malta. In: Kuroiwa Y, Kurland LT (eds) Multiple sclerosis east and west. Kyushu University Press, Fukuoka, pp 195–200

    Google Scholar 

  11. Dean G (1984) Epidemiology of multiple sclerosis. Neuroepidemiology 3: 58–73

    Article  Google Scholar 

  12. Dean G, Goodall J, Downie A (1981) The prevalence of multiple sclerosis in the Outer Hebrides compared with North-east Scotland and the Orkney and Shetland islands. J Epidemiol Community Health 35: 110–113

    Article  PubMed  CAS  Google Scholar 

  13. Dean G, Grimaldi G, Kelly R, Karhausen L (1979) Multiple sclerosis in Southern Europe I. Prevalence in Sicily in 1975. J Epidemiol Community Health 33: 107–110

    Article  PubMed  CAS  Google Scholar 

  14. Detels R, Brody JA, Edgar AH (1972) Multiple sclerosis among American Japanese and Chinese migrants to California and Washington. J Chron Dis 25: 3–10

    Article  PubMed  CAS  Google Scholar 

  15. Granieri E, Rosati G (1982) Italy: a medium- or high-risk area for multiple sclerosis, an epidemiologic study in Barbagia Sardinia southern Italy. Neurology 32: 466–472

    PubMed  CAS  Google Scholar 

  16. Gyodi E, Tauszik T, Petränyi Gy, Kotväsz Á, Pálffy G, Takäcs I, Nemäk P, Hollän SR (1981) The HLA antigen distribution in the gipsy population in Hungary. Tissue Antigens 18: 1–12

    Article  PubMed  CAS  Google Scholar 

  17. Ishohara O, Yamaguchi Y, Matsuishi T et al. (1984) Multiple ring enhancement in a case of acute reversible demyelinating disease in childhood suggestive of acute multiple sclerosis. Brain Dev 6: 401–406

    Google Scholar 

  18. Jokelainen M, Wikström J, Palo J (1984) Effect of birthplace on the development of amyotrophic lateral sclerosis and multiple sclerosis. A study among Finnish war evacuees. Acta Neurol Scand 60: 283–288

    Google Scholar 

  19. Környey S (1952) Early stage of Schilder’s disease and relation to other forms of leucoencephalitis. Arch Neurol Psychiatr 68: 683–697

    Google Scholar 

  20. Kranz JS, Kurland LT (1982) General overview of the epidemiology of multiple sclerosis with emphasis on the geographic pattern and long-term trends. In: Kuroiwa Y, Kurland LT (eds) Multiple sclerosis east and west. Kyushu University Press, Fukuoka, pp 3–29

    Google Scholar 

  21. Kurland LT, Molgaard CA, Kurland EM, Wiederholt WC, Kirkpatrick JW (1984) Swine flu vaccine and multiple sclerosis. JAMA 25: 2672–2675

    Article  Google Scholar 

  22. Kuroiwa Y, Shibasaki H, Ikeda M (1983) Prevalence of multiple sclerosis and its north-to south gradient in Japan. Neuroepidemiology 2: 62–69

    Article  Google Scholar 

  23. Kuroiwa Y, Shibasaki H, Tabira T, Itoyama Y (1982) Clinical picture of multiple sclerosis in Asia. In: Kuroiwa Y, Kurland LT (eds) Multiple sclerosis east and west. Kyushu University Press, Fukuoka, pp 32–42

    Google Scholar 

  24. Kurtzke JF (1980) Multiple sclerosis, an overview. In: Rose FC (ed) Clinical neuroepidemiology. Pitman Medical, Bath, pp 170–195

    Google Scholar 

  25. Kurtzke JF, Hyllested K (1982) MS in the Faroes, an update. In: Kuroiwa Y, Kurland LT (eds) Multiple sclerosis east and west. Kyushu University Press, Fukuoka, pp 183–194

    Google Scholar 

  26. Larsen JP, Kvaale G, Riise T et al. (1984) An increase in the incidence of multiple sclerosis in western Norway. Acta Neurol Scand 70: 96–103

    Article  PubMed  CAS  Google Scholar 

  27. Lauer K, Firnhaber W (1984) Epidemiological investigations into multiple sclerosis in southern Hesse. II. The distribution of cases in relation to exogenous factors. Acta Neurol Scand 70: 266–273

    Google Scholar 

  28. Lehoczky T, Lehoczky-Halassy M (1961) Multiple sclerosis in Hungary. World Neurol 2: 38–44

    PubMed  CAS  Google Scholar 

  29. Leibowitz U, Kahana E, Alter M (1973) The changing frequency of multiple sclerosis in Israel. Arch Neurol 29: 107–110

    PubMed  CAS  Google Scholar 

  30. Lowe RF, Moore HH, Briggs BR (1980) The histocompatibility (HLA) antigen distribution in multiple sclerosis patients in Zimbabwe Centr. Afr. J Med 26: 234–236

    Google Scholar 

  31. Materljan (1983) Epidemiology of multiple sclerosis in Istria (in Kroatian). Thesis, Medical faculty of the University Rijeka (summary in English)

    Google Scholar 

  32. McDonald MI (1984) Multiple sclerosis epidemiology and HLA associations. Ann NY Acad Sci 436: 109–117

    Article  PubMed  CAS  Google Scholar 

  33. Meyer-Rienecker HJ, Buddenhagen F (1983) Grundlagen und Problematik der Epidemiologie der Multiplen Sklerose. Psychiatr Neurol Med Psychol 35: 697–707

    Google Scholar 

  34. G (1954) Neurologie complications following the use of sera and vaccines. Acta Med Acad Sei Hung 5: 403–411

    Google Scholar 

  35. Pálffy G (1980) Some features of MS in Pecs, Hungary. In: Bauer HJ, Poser S, Ritter G (eds) Progress in multiple sclerosis research. Springer, Berlin Heidelberg New York, pp 549–550

    Google Scholar 

  36. Pállfy G (1982) MS in Hungary including the Gipsy population. In: Kuroiwa Y, Kurland LT (eds) Multiple sclerosis east and west. Kyushu University Press, Fukuoka, pp 149–157

    Google Scholar 

  37. Pálffy G (1982) The prevalence of multiple sclerosis in Pecs, Hungary.Ideggyögy Szle/ Hung Neurol Rev 12-17 (in Hungarian with summary in Russian and in German)

    Google Scholar 

  38. Pálffy G, Merei FT (1961) The possible role of vaccines and sera in the pathogenesis of multiple sclerosis. World Neurol 2: 167–171

    PubMed  Google Scholar 

  39. Petrescu A (1977) Date actuale de epidemiologic a sclerosis multiple. Neurol Psychiat Neurochir 22: 175–188

    CAS  Google Scholar 

  40. Shepherd DI, Downie AW (1980) A further prevalence study of multiple sclerosis in northeast Scotland. J Neurol Neurosurg Psychiatry 43: 310–315

    Article  PubMed  CAS  Google Scholar 

  41. Shibasaki H, McDonald WI, Kuroiwa Y (1981) Racial modification of clinical picture of multiple sclerosis. J Neurol Sci 49: 253–271

    Article  PubMed  CAS  Google Scholar 

  42. Singhai ES, Wadia NH (1975) Profile of multiple sclerosis in the Bombay region on the basis of critical clinical appraisal. J Neurol Sci 26: 259–270

    Article  Google Scholar 

  43. Trikannad VS, Wadia NH, Krishnaswany FR (1982) Multiple sclerosis and HLA B12 in Parsi and non-Parsi Indians. A clarification. Tissue Antigens 19: 155–157

    Google Scholar 

  44. Tsu-Pei Hung (1982) Multiple sclerosis in Taiwan. A reappraisal. In: Kuroiwa Y, Kurland LT (eds) Multiple sclerosis east and west. Kyushu University Press, Fukuoka, pp 83–96

    Google Scholar 

  45. Viischer BR, Bunnel DH, Detels R (1981) Multiple sclerosis and multiple moves. An etiologic hypothesis. Am J Epidemiol 132: 140–143

    Google Scholar 

  46. Wadia NH, Trikannad VS, Krishnaswamy PR (1981) HLA antigens in multiple sclerosis amongst Indians. J Neurol Neurosurg Psychiatry 44: 849–851

    Article  PubMed  CAS  Google Scholar 

  47. Wikström J, Palo J (1976) Studies on the geographic clustering of multiple sclerosis and optic neuritis in Finland. J Neurol 213: 79–85

    Article  PubMed  Google Scholar 

  48. Wikström J, Ritter G, Poser S, Firnhaber W, Bauer HJ (1977) Das Vorkommen von Multipler Sklerose in Südniedersachsen. Ergebnisse einer Feldstudie über 12 Jahre. Nervenarzt 48: 494–499

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1986 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Pálffy, G. (1986). Epidemiology of Multiple Sclerosis. In: Poeck, K., Freund, HJ., Gänshirt, H. (eds) Neurology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70007-1_38

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-70007-1_38

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-70009-5

  • Online ISBN: 978-3-642-70007-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics