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Detection of Group A Streptococcal Antigen by Coagglutination and Latex Agglutination

  • M. A. Gerber
Conference paper

Abstract

The original method for the serological grouping of streptococci was developed by Lancefield [21] and involved hot-acid extraction of group-specific antigen followed by precipitin testing with group-specific antisera in capillary tubes. Over the years, this method has been modified by the use of several different extraction procedures, including hot-formamide extraction [16], autoclaving [28], nitrous acid extraction [12], Streptomyces albus lytic enzyme extraction [24], and pronase B extraction [9]. In addition to the classical method of serogrouping by precipitation, fluorescent-antibody techniques have also been developed [26]. While accurate and reliable, all of these methods are relatively laborious, time consuming, and require well-trained laboratory personnel.

Keywords

Blood Agar Latex Agglutination Blood Agar Plate Throat Swab Latex Agglutination Test 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1985

Authors and Affiliations

  • M. A. Gerber
    • 1
  1. 1.Department of PediatricsUniversity of Connecticut School of MedicineFarmingtonUSA

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