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A Direct Correlation Between the Affinity of a Given mRNa for Eukaryotic Initiation Factor 2 and its Ability to Compete in Translation

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Mechanisms of Protein Synthesis

Part of the book series: Proceedings in Life Sciences ((LIFE SCIENCES))

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Abstract

Eukaryotic gene expression is often regulated by the selective translation of specific mRNA templates over other ones. Examples of this type of control, involving competition between mRNA species, are encountered in cellular differentiation and virus infection. Messenger RNA competition is thought to occur mainly at initiation of translation, during the recognition of mRNA and its binding to ribosomes.

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Author information

Authors and Affiliations

  1. Department of Molecular Virology, The Hebrew University-Hadassah Medical School, 91 010, Jerusalem, Israel

    R. Kaempfer, H. Rosen & G. Di Segni

Authors
  1. R. Kaempfer
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  2. H. Rosen
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  3. G. Di Segni
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Editors and Affiliations

  1. Biyofizik Bilim Dali, Istanbul Tip Fakültesi, Istanbul Üniversitesi, Çapa, Istanbul, Türkiye

    Engin Bermek

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© 1984 Springer-Verlag, Berlin Heidelberg

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Kaempfer, R., Rosen, H., Di Segni, G. (1984). A Direct Correlation Between the Affinity of a Given mRNa for Eukaryotic Initiation Factor 2 and its Ability to Compete in Translation. In: Bermek, E. (eds) Mechanisms of Protein Synthesis. Proceedings in Life Sciences. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69912-2_9

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  • DOI: https://doi.org/10.1007/978-3-642-69912-2_9

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-69914-6

  • Online ISBN: 978-3-642-69912-2

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