Studies on Structural Dynamics of the Translating Ribosome
The process of translation (elongation) on the ribosome is composed of the repeating cycles, each consisting of three successive steps: aminoacyl-tRNA binding, transpeptidation, and translocation (Watson 1964; Lipmann 1969). The translocation step includes significant intraribosomal displacements of a template and the products of the transpeptidation reaction: the release of deacylated tRNA, the transport of peptidyl-tRNA from one site to the other, and the shift of the template polynucelotide by one codon.
KeywordsSucrose Codon Sedimentation Polypeptide Disulfide
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