Studies on Structural Dynamics of the Translating Ribosome

  • A. S. Spirin
  • I. N. Serdyuk
Part of the Proceedings in Life Sciences book series (LIFE SCIENCES)


The process of translation (elongation) on the ribosome is composed of the repeating cycles, each consisting of three successive steps: aminoacyl-tRNA binding, transpeptidation, and translocation (Watson 1964; Lipmann 1969). The translocation step includes significant intraribosomal displacements of a template and the products of the transpeptidation reaction: the release of deacylated tRNA, the transport of peptidyl-tRNA from one site to the other, and the shift of the template polynucelotide by one codon.


Neutron Scattering Sedimentation Coefficient Elongation Cycle Guanosine Triphosphatase Guinier Plot 
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Copyright information

© Springer-Verlag, Berlin Heidelberg 1984

Authors and Affiliations

  • A. S. Spirin
    • 1
  • I. N. Serdyuk
    • 1
  1. 1.Institute of Protein ResearchAcademy of Sciences of the USSRPushchino, Moscow RegionUSSR

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