Abstract
In trying to establish a system for the study of myc-induced in vitro transformation of mammalian cells, we have constructed a mammalian retrovirus encoding an avian myc oncogene. Its LTRs are derived from the Moloney Murine Leukemia Virus (MoMuLV) and the myc oncogene from the avian retrovirus OK10. A virus, denoted murine myc virus (MMCV), was recovered after cotransfecting NIH3T3 cells with MMCV and MoMuLV helper virus DNAs.
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© 1984 Springer-Verlag Berlin · Heidelberg
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Vennström, B. et al. (1984). Transformation Capacities of a Murine Retrovirus Encoding an Avian myc Oncogene. In: Potter, M., Melchers, F., Weigert, M. (eds) Oncogenes in B-Cell Neoplasia. Current Topics in Microbiology and Immunology, vol 113. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69860-6_42
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DOI: https://doi.org/10.1007/978-3-642-69860-6_42
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-69862-0
Online ISBN: 978-3-642-69860-6
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