myc-Encoded Proteins of Chickens and Men
Recent work from many laboratories has demonstrated that the chromosomal locus containing the myc oncogene is the site of an extraordinary number of rearrangements. These rearrangements take the form of translocations, amplifications, and retroviral insertions and examples have been found in chickens, mice, and humans. In addition, such alterations in the myc locus appear to be associated with neoplasias of primarily lymphoid origin although myc amplification has also been observed in human neuroendocrine tumors and small cell lung carcinomas (see other papers in this volume).
KeywordsSmall Cell Lung Carcinoma Normal Human Lung Cell Human Neuroendocrine Tumor Acid Precipitable Radioactivity Altered Nucleotide Sequence
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