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Prostaglandine, Entzündungen und die Wirkung antiphlogistischer Analgetika

  • Conference paper
Pathobiochemie der Entzündung

Part of the book series: Zusammenarbeit von Klinik und Klinischer Chemie ((ZUSAMMENARBEIT))

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Zusammenfassung

In den vergangenen Jahren hat die Konzeption, daß antiphlogistische Analgetika aufgrund der Hemmung der Prostaglandinsynthese wirken, eine zentrale Rolle gespielt. Dieses Konzept hat nicht in jeder Beziehung befriedigen können; denn die “stabilen” Prostaglandine sind keine entscheidenden Entzündungsmediatoren, und die Hemmung ihrer Synthese allein erklärt die Wirksamkeit und die Nebenwirkungen der nichtsteroidalen antiphlogistischen Analgetika nicht. Alternative und ergänzende Konzepte müssen daher in Betracht gezogen werden.

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Authors
  1. K. Brune
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Editors and Affiliations

  1. Biochemische Forschung E. Merck, Darmstadt, Deutschland

    Hermann Lang

  2. Lehrstuhl für Klinische Chemie und Pathobiochemie, Klinisch-Chemisches Zentrallaboratorium, Medizinische Fakultät der RWTH, Aachen, Deutschland

    Helmut Greiling

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© 1984 Springer-Verlag Berlin · Heidelberg

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Brune, K. (1984). Prostaglandine, Entzündungen und die Wirkung antiphlogistischer Analgetika. In: Lang, H., Greiling, H. (eds) Pathobiochemie der Entzündung. Zusammenarbeit von Klinik und Klinischer Chemie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69826-2_4

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  • DOI: https://doi.org/10.1007/978-3-642-69826-2_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-13533-3

  • Online ISBN: 978-3-642-69826-2

  • eBook Packages: Springer Book Archive

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