Abstract
The effect of caffeine on the heart and blood vessels has attracted the attention of investigators for more than 100 years. The earliest studies are reviewed in some detail by Bock (1920) and Eichler (1938). In the second edition of his monograph on caffeine, Eichler (1976) reviewed the literature on the cardiovascular effects of caffeine up to the year 1974. Much of the available data comes from animal studies. In some cases the human pharmacology of caffeine has been inferred from studies with theophylline. The first part of this chapter will deal with in vitro and animal studies. In the last part of the chapter the effects of the drug in man will be treated.
The author’s work was supported in part by US Public Health Service grants HL 14192 and GM 15431 and by grants from the Hrafn Sveinbjarnrson Foundation and the International Life Sciences Institute. Dr. Robertson is the recipient of a Research Career Development Award from the National Institute of Health.
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Robertson, D., Curatolo, P.W. (1984). The Cardiovascular Effects of Caffeine. In: Dews, P.B. (eds) Caffeine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69823-1_5
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DOI: https://doi.org/10.1007/978-3-642-69823-1_5
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