Bestimmung von Zink in Thrombocyten mit INAA und AAS

  • J. Kiem
  • H. Weese
  • L. E. Feinendegen
Conference paper


To clarify discrepancies in the literature we determined the concentration of zinc in normal human platelets using instrumental neutron activation analysis (INAA, n = 26) and atomic absorption spectrophotometry (AAS, n = 5 × 6). We detected the following sources of error: zinc contamination, erroneous platelet wet weight, errors when using INAA. Additionally, we determined the concentrations of calcium and magnesium in the AAS-samples (n = 5 × 6). We observed that after elimination of the sources of error the normal ranges (mean ± 2 SD) for the elements zinc, calcium and magnesium are far closer than hitherto believed. Based on platelet wet weight corrected for plasma, they are: Zn = 26.5–32.3 µg/g; Ca = 567–693 µg/g, Mg = 178–218µg/g.


Zinc Contamination Normal Human Platelet 
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Copyright information

© Springer-Verlag 1984

Authors and Affiliations

  • J. Kiem
    • 1
  • H. Weese
    • 1
  • L. E. Feinendegen
    • 1
  1. 1.Institut für MedizinKernforschungsanlage Jülich GmbHJülichBundesrepublik Deutschland

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