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Antigen Report: HLA-DRw8

  • H. Bétuel
  • L. Gebuhrer
  • G. M. T. Schreuder
  • Z. Layrisse
  • A. Arnaiz Villena
  • S. F. Goldmann

Abstract

The definition of DRw8 at the last Histocompatibility Workshop was based on the reactions of five sera with r values between 0.40 and 0.58 [1]. For this Workshop, analysis of DRw8 was studied in relation to DR5 and DRw6. More extensive serum reaction patterns are presented in all three reports to permit a better comparison of these cross-reacting specificities (Table 1). The segregation pattern of the sera shown in Table 1 were studied in informative Workshop families. The mode of selection is given in details in the Joint Reports on DR5 (Bétuel et al., this volume) and on DRw6 (Schreuder et al., this volume). Examples of such haplotypes are presented in Table 2. Several DRw8-related patterns were observed in which all DRw52 (MT2), DR5 + w8 + w13 (6.6) and DRw8 sera were positive.

Keywords

Percent Percent Joint Report Royal Perth Hospital Percent Percent Percent Extra Reaction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Dausset J (1980) Drw8. Joint report. In: Terasaki PI (ed) Histocompatibility testing 1980. UCLA Tissue Typing Laboratory, Los Angeles, pp 538–540Google Scholar
  2. 2.
    Nakata S, Park MS, Terasaki PI, Omori K (1980) 8wDRw17. Joint report. In: Terasaki PI (ed) Histocompatibility testing 1980. UCLA Tissue Typing Laboratory, Los Angeles, pp 548–550Google Scholar
  3. 3.
    Termijtelen A, Boettcher B, Bradley BA, D’Amaro J, Van Leeuwen A, Van Rood JJ (1980) DR typing in Australian aborigines: an indication for a second locus in the HLA-D region defined by serology. Tissue Antigens 16: 140PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1984

Authors and Affiliations

  • H. Bétuel
    • 1
  • L. Gebuhrer
    • 1
  • G. M. T. Schreuder
    • 2
  • Z. Layrisse
    • 3
  • A. Arnaiz Villena
    • 4
  • S. F. Goldmann
    • 5
  1. 1.Histocompatibility LaboratoryBlood Transfusion CenterLyonFrance
  2. 2.Dept. of Immunohematology, Blood BankUniversity HospitalLeidenThe Netherlands
  3. 3.Instituto Venezolano de Investigaciones CientificasCaracasVenezuela
  4. 4.Sce. Imuno. Cent. Especial Ramon y CajalMadridSpain
  5. 5.Dept. of Transplantation ImmunologyRed Cross Blood BankUlmFederal Republic of Germany

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