Antigen Report: HLA-DR2

  • J. R. Batchelor
  • J. Hors
  • I. A. Dodi
  • H. Bétuel
  • I. Borelli

Abstract

At the Eighth International Histocompatibility Workshop, Lawler and Dewar [7] concluded that DR2 was a well-defined antigen, and claims of splits awaited further confirmation. Since then, heterogeneity of DR2 has been further documented [8]. Gebuhrer et al. [4] divided DR2 into a long DR2 identified by positive reactions with all the Ninth Workshop DR2 sera including 9w555, and a short variant, DR2S, defined by positive reactions with all the DR2 antisera except 9w555. These findings have been confirmed in other laboratories [5, 9]. Two other variants have been claimed. DR2 Lum [9] was identified in South African Negroes by positive reactions with all the Ninth Workshop DR2 sera except 9w542 and 543. The other split, FT31 [5], has been observed in Chinese and was identified by positive reactions with all the Ninth Workshop DR2 sera except 9w546–550.

Keywords

Bete 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1984

Authors and Affiliations

  • J. R. Batchelor
    • 1
  • J. Hors
    • 2
  • I. A. Dodi
    • 1
  • H. Bétuel
    • 3
  • I. Borelli
    • 4
  1. 1.Department of Immunology, Royal Postgraduate Medical SchoolHammersmith HospitalLondonUK
  2. 2.INSERM U.93Hôpital St LouisParisFrance
  3. 3.Centre de Transfusion SanguineLyonFrance
  4. 4.Istituto de Genetica Medica Università di TorinoTorinoItaly

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