Antigen Report: HLA-Bw73
This antigen, originally described by Mayr and Kirnbauer , has been assigned in 17–21 cells of the 5000 cell panel. Three sera, 9w245, 9w246 and 9w247, have Q scores between 7.5 and 6.0. They all miss approximately 20% of Bw73-positive cells, but at least two of these three sera react with all the cells. The three sera all contain anti-B7, anti-B27, and anti-Bw22 components. Thus, Bw73 can only be properly assigned on cells negative for these antigens. Serum 9w479 may be helpful, since in addition to Bw73 it contains anti-Cw4 and anti-Cw6 components, but not B7, B27 and Bw22 components. Furthermore, in some laboratories serum 9w440 behaved as an operationally specific anti-Bw73. Similar patterns were found in Caucasians and Negroes.
KeywordsHistocompatibility Testing African Black Patient Transfusion Sanguine Tissue Type Laboratory Blood Group Serology
- 1.Mayr WR, Kirnbauer M (1981) Rare HLA-A, B, C antigens in Caucasoids. In: Steinberg C, Lefkovits L (eds) The immune system, vol 2. Karger, Basel, pp 217–223Google Scholar