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Antigen Report: HLA-Aw43

  • E. M. Campbell
  • E. D. du Toit
  • M. G. Hammond
  • M. Oudshoorn

Abstract

In 1972, the occurrence of apparent triplets associated with HLA-A10 and A29 in the Khoisan populations of Namibia was reported [1]. In 1975 [6], an HLA-A10/A29 allele was defined in terms of the Fifth International Histocompatibility Workshop antisera and designated BK. The Sixth and Seventh Workshops [2, 3] provided further opportunities for studying BK. At both these workshops BK was serologically well defined with reactions involving HLA-A10, A26, and A29 antisera and was shown to segregate clearly within families. During the Eighth Workshop a monospecific HLA-Aw43 antibody was used for the first time, simplifying the assignment of this antigen [4]. Although at the time of the Eighth Workshop, HLA-Aw43 had only been found in Khoisan, Cape Colored, Xhosa, and South African Caucasoid individuals in Cape Town [4], we felt that HLA-Aw43 would eventually be detected in other Southern African groups.

Keywords

International Histocompatibility Workshop Histocompatibility Testing Tissue Type Laboratory Seventh Workshop UCLA Tissue Type Laboratory 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Botha MC, du Toit ED, Jenkins T, van Leeuwen A, D’Amaro J, Meera Khan P, van der Steen G, van Rood JJ, van der Does J (1972) The HL-A system in Bushmen (San) and Hottentot (Khoikhoi) populations of South West Africa. In: Dausset J, Colombani J (eds) Histocompatibility testing 1972. Munksgaard, Copenhagen, p 421Google Scholar
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    Du Toit ED, Briggs BR, Botha MC, Campbell EM (1980) Joint Report. HLA-Aw43. In: Terasaki P (ed) Histocompatibility testing 1980. UCLA Tissue Typing Laboratory, Los Angeles, p 344Google Scholar
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    Nurse GT, Bodmer JG, Bodmer WF, van Leeuwen A, van Rood JJ, du Toit ED, Botha MC (1975) A reassessment of HL-A system in Khoisan populations in South West Africa. Tissue Antigens 5:402PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1984

Authors and Affiliations

  • E. M. Campbell
    • 1
  • E. D. du Toit
    • 1
  • M. G. Hammond
    • 2
  • M. Oudshoorn
    • 1
  1. 1.Provincial Laboratory for Tissue ImmunologyObservatorySouth Africa
  2. 2.Natal Institute of ImmunologyDurbanSouth Africa

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