Abstract
Class II major histocompatibility antigens (MHC) play a fundamental role for both antigen presentation to T cells and stimulation in mixed lymphocyte reactions. Recent progress in the understanding of human class II MHC antigens has provided evidence for at least three types of Ia molecules:HLA-DR,DQ, and DP.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Frelinger JA (1982) Tissue distribution and cellular expression of la antigens. In: Ferrone S, David CS (eds) Antigens, vol 1. CRC Press, Boca Raton, pp 37–54
Cowing C, Schwartz BD, Dickler HB (1978) Macrophage la antigens. I. Macrophage populations differ in their expression of la antigens. J Immunol 120: 378–384
Pettinelli CB, Ahmann GB, Shearer G (1980) Expression of both I-A and I-E/C subregion antigens on accessory cells required for in vitro generation of cytotoxic T lymphocytes against alloantigens or TNBS-modified syngeneic cells. J Immunol 124: 1911–1916
Gonwa T, Picker L, Raff H, Goyert S, Silver J, Stobo J (1983) Antigen-presenting capabilities of human monocytes correlates with their expression of HLA-DS, an la determinant distinct from HLA-DR. J Immunol 130: 706–711
Nuñez G, Giles RC, Ball EJ, Hurley CK, Capra JD, Stastny P (1984) Expression of HLA-DR, MB, MT, and SB antigens on human mononuclear cells: identification of two phenotypically distinct monocyte populations. J Immunol 133: 1300–1306
Nuñez G, Stastny P (1983) Cytofluorometric analysis of major histocompatibility antigens on human monocytes using monoclonal antibodies. Hum Immunol 6: 1–11
Myers LK, Ball EJ, Stastny P (1984) Different specificities of an HLA-DRw6 haplotype detected by alloreactive T lymphocytes. Hum Immunol (in press)
Basham TY, Merigan TC (1983) Recombinant interferon- gamma increases HLA-DR synthesis and expression. J Immunol 130: 1492–1494
Natali PG, Segatto O, Ferrone S, Tosi R, Corte G (1984) Differential tissue distribution and ontogeny of DC-1 and HLA-DR antigens. Immunogenetics 19:109–116
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1984 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Nunez, G., Ball, E.J., Myers, L.K., Stastny, P. (1984). Expression of HLA-DQ Molecules on Human Monocytes: Identification of Two Phenotypically Different Monocyte Populations with Distinct Accessory Cell Function. In: Albert, E.D., et al. Histocompatibility Testing 1984. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69770-8_242
Download citation
DOI: https://doi.org/10.1007/978-3-642-69770-8_242
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-69772-2
Online ISBN: 978-3-642-69770-8
eBook Packages: Springer Book Archive