The Expression of HLA-DR, DQ and DP Antigens on the Surface of Lymphocytes as Assessed by 2-D Polyacrylamide Gel Analysis of Immunoprecipitates

  • C. E. Rudd
  • J. G. Bodmer
  • W. F. Bodmer
  • M. J. Crumpton
Conference paper


The HLA-D region of the human major histocompatibility complex (MHC) encodes for several sets of class II antigens involved in regulating immune responses. At least three distinct subregions have been distinguished (namely HLA-DR, DQ, DP) by a combination of serology, immunoprecipitation and cellular responses [1–3].


Major Histocompatibility Complex WT46 Cell Neuraminidase Digestion Cell Line WT46 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1984

Authors and Affiliations

  • C. E. Rudd
    • 1
  • J. G. Bodmer
    • 1
  • W. F. Bodmer
    • 1
  • M. J. Crumpton
    • 1
  1. 1.Imperial Cancer Research FundLondonUK

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