HLA-FA: A Non-DR, Non-DQ HLA Class II Product

  • K. M. Linner
  • F. H. Bach


We have used a monoclonal antibody (mcAb) supplied by Dr. Ian Trowbridge to define a non-DR, non-DQ HLA class II molecule which we have provisionally termed HLA-FA; certain features of this molecule are unusual as compared with HLA-DR and HLA-DQ [1], First, there is a molecular weight polymorphism of the FA β chain, ranging from 25K to 27K; second, the FA α chain is virtually inaccessible to lactoperoxidase-catalyzed iodination (125I), though it can be readily visualized with metabolic labeling.


Migration Iodi Polypeptide 


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Copyright information

© Springer-Verlag Berlin Heidelberg 1984

Authors and Affiliations

  • K. M. Linner
    • 1
  • F. H. Bach
    • 1
  1. 1.Dept. of Lab. Medicine and PathologyMinneapolisUSA

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