Advertisement

Serological and Structural Heterogeneity of HLA-DR4 Alloantigens

  • M. Igarashi
  • M. Yoshii
  • N. Kashiwagi
  • T. Crepaldi
  • S. Ferrone
Conference paper

Abstract

Testing of a large panel of anti-class II monoclonal antibodies (MoAb) with the lymphoid cell lines FS, L-KT9, L-KT13, THO, and WALK carrying serologically indistinguishable DR4 allospecificities but different cellularly defined HLA-D allospecificities showed that the anti-HLA-DR MoAb Q2/80 displayed differential reactivity with the cell lines (Table 1).

Keywords

Chronic Lymphocytic Leukemia Molecular Polymorphism National MUltiple Sclerosis Society Dime Birth Defect Foundation Significant Difference Table 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Groner JP, Watson AJ, Bach FH (1983) Dw/LD-related molecular polymorphism of DR4 β-chains. J Exp Med 157: 1687–1691PubMedCrossRefGoogle Scholar
  2. 2.
    Nepom BS, Nepom GT, Mickelson E, Antonelli P, Hansen JA (1983) Electrophoretic analysis of human HLA- DR antigens from HLA-DR4 homozygous cell lines: Correlation between β-chain diversity and HLA-D. Proc Natl Acad Sci USA 80: 6962–6966PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1984

Authors and Affiliations

  • M. Igarashi
    • 1
  • M. Yoshii
    • 2
  • N. Kashiwagi
    • 2
  • T. Crepaldi
    • 1
  • S. Ferrone
    • 1
  1. 1.Dept. of Microbiology and ImmunologyNew York Medical CollegeValhallaUSA
  2. 2.Dept. of Transplantation ImmunologyKitasato University, School of MedicineSagamihara, KanagawaJapan

Personalised recommendations