Construction and Expansion of CTLs for HLA Typing: Definition of B44 Subtypes by Cellular Typing
The polymorphic gene products of the human HLA region can be identified both by serological and cellular typing techniques. Although the definition of the system, its loci, and their antigenic determinants is in essence based on serological studies and analyses, it is now evident that a determinant primarily described by one technique, e.g., serology, may be detected similarly by the other, viz cellular typing (MLC, PLT, or CML). Thus, serological and cellular typing studies are equally precise with regard to specificity and must supplement each other.
KeywordsCellular Typing Lysed Target Cell Negative Target Percentage Cytotoxicity Reciprocal Combination
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