PLT Analysis of D Region Complexity by Cloned Cells: A New Non-DP Antigen
The HLA-D region is very complex. HLA-D specificity is not identical to DR. It is not known whether the difference in HLA-D of cells with the same DR can be supposed to be due to one antigen determinant. To resolve the problem, PLT clones were used. From the MLC of cells with the same DR, DQ, DP antigens but with different D antigens, Dwl5-specific PLT clones and a Dw4-specific clone were established.
KeywordsChronic Lymphocytic Leukemia Antigen Determinant Clone Class Antigen Phenotype International Histocompatibility Workshop
Unable to display preview. Download preview PDF.
- 1.Inouye H, Hank JA, Chardonnens X, Segall M, Alter BJ, Bach FH (1980) Cloned primed-lymphocyte-test reagent in the dissection of HLA-D. J Exp Med 152: 143s–155sGoogle Scholar