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Histocompatibility Testing 1984 pp 432Cite as

Serological Analysis of Two Monoclonal Antibodies: One Detecting an DRw53 Supertypic Determinant and One Detecting a New Supertypic Determinant Related to HLA-DR7

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Abstract

Two cytotoxic monoclonal antibodies (MoAbs), PL3 (IgG3) and PL2 (IgG2a), were produced by immunization with an HLA-DR7 homozygous cell line, PLH. Their serological specificities were determined by binding assays and by complement-dependent microcytotoxicity on an extensive cell panel.

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Author information

Authors and Affiliations

  1. Sloan-Kettering Memorial Cancer Center, Box 41, 1275 York Avenue, New York, NY, 10021, USA

    K. Horibe, R. W. Knowles, M. S. Pollack & B. Dupont

Authors
  1. K. Horibe
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  2. R. W. Knowles
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  3. M. S. Pollack
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  4. B. Dupont
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Editor information

Editors and Affiliations

  1. Labor für Immungenetik, Kinderpoliklinik der Universität, Pettenkoferstraße 8a, 8000, München 2, Bundesrepublik Deutschland

    Ekkehard D. Albert

  2. Biometrische Abteilung, Diabetes Forschungsinstitut an der Universität, Auf’m Hennekamp 65, 4000, Düsseldorf 1, Bundesrepublik Deutschland

    Max P. Baur

  3. Institut für Blutgruppenserologie der Universität, Spitalgasse 4, 1090, Wien, Österreich

    Wolfgang R. Mayr

  4. Essen, Germany

    J. Bertrams  & H. Grosse-Wilde  & 

  5. Ulm, Germany

    S. Goldmann

  6. Heidelberg, Germany

    G. Opelz

  7. Bonn, Germany

    C. Rittner

  8. Munich, Germany

    D. J. Schendel , S. Scholz  & R. Wank ,  & 

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© 1984 Springer-Verlag Berlin Heidelberg

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Cite this paper

Horibe, K., Knowles, R.W., Pollack, M.S., Dupont, B. (1984). Serological Analysis of Two Monoclonal Antibodies: One Detecting an DRw53 Supertypic Determinant and One Detecting a New Supertypic Determinant Related to HLA-DR7. In: Albert, E.D., et al. Histocompatibility Testing 1984. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69770-8_145

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  • DOI: https://doi.org/10.1007/978-3-642-69770-8_145

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-69772-2

  • Online ISBN: 978-3-642-69770-8

  • eBook Packages: Springer Book Archive

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