Leprosy is a chronic infectious disease which presently affects more than 15 million individuals. The disease is the result of the interaction between Mycobacterium leprae and the immune system of the infected host, M. leprae by itself being a virtually harmless bacillus. Apparently the majority of individuals exposed to or infected with M. leprae develops effective immunity to M. leprae without disease. A minority, however, may develop a wide range of clinical symptoms, which show striking interindividual variability. This clinical spectrum closely parallels the immunological spectrum of responsiveness displayed by the host [1,2].
KeywordsFiltration Recombination Tuberculosis Bacillus Rosen
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