Dynamic Liver CT and New Contrast Agents

  • M. Kormano
  • K. Partanen
  • J. Kuikka
Part of the Radiology Today book series (RADIOL.TODAY, volume 3)


The technique of performing rapid sequential CT scans after a bolus of contrast medium (CM) is commonly called dynamic CT scanning. The ability of dynamic CT to produce images at the time of maximal contrast enhancement (CE), which occurs at varying times in the normal liver, in hepatic lesions, and in adjoining organs, has brought an improvement in imaging and diagnosis of localized liver lesions as reported by several authors [1, 4, 5, 14, 15, 16, 21, 22, 23]. Intra-arterial injection of CM would improve the diagnostic ability of dynamic liver CT [16], but for practical reasons intravenous injections are the common method in dynamic CT.


Cavernous Hemangioma Liver Blood Flow Streak Artifact Nonionic Contrast Medium Diffuse Liver Disease 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. 1.
    Araki T, Itai Y, Furni S, Tasaka A (1980) Dynamic CT densitometry of hepatic tumors. AJR 135: 1037–1043PubMedGoogle Scholar
  2. 2.
    Axel L, Dean PB, Moss AA, Stansberry D (1984) Functional imaging of the liver. New information from dynamic CT. Invest Radiol 19: 23–29PubMedCrossRefGoogle Scholar
  3. 3.
    Barnett PH, Zerhouni EA, White RI Jr, Siegelman SS (1980) Computed tomography in the diagnosis of cavernous hemangioma of the liver. AJR 134: 439–447PubMedGoogle Scholar
  4. 4.
    Burgener FA, Hamlin DJ (1983) Contrast enhancement of hepatic tumors in CT: comparison between bolus and infusion techniques. AJR 140: 291–295PubMedGoogle Scholar
  5. 5.
    Burgener FA, Hamlin DJ (1983) Contrast enhancement of focal lesions in CT: effect of size and histology. AJR 140: 297–301PubMedGoogle Scholar
  6. 6.
    Dean PB, Kivisaari L, Kormano M (1983) Contrast enhancement pharmacokinetics of six ionic and nonionic contrast media. Invest Radiol 18: 368–374PubMedCrossRefGoogle Scholar
  7. 7.
    Härtel M (1980) Das kavernöse Leberhämangiom im Computertomogramm. ROFO 133: 379–381CrossRefGoogle Scholar
  8. 8.
    Hübener K-H, Klott KJ (1980) Statisches und dynamisches Kontrastmittelenhancement der Körperstamm-Computertomographie. ROFO 133: 347–354PubMedCrossRefGoogle Scholar
  9. 9.
    Hübener K-H, Kurtz B (1984) Sequentielle Com-putertomographie bei fokalen und diffusen Lebererkrankungen. Paper presented at congress on computed tomography, May 23–25, East BerlinGoogle Scholar
  10. 10.
    Itai Y, Furvi S, Araki T, Yashiro N, Tasaka A (1980) Computed tomography of cavernous hemangioma of the liver. Radiology 137: 149–155PubMedGoogle Scholar
  11. 11.
    Kormano M (1981) Kinetics of contrast media after bolus injection and infusion. In: Felix R, Kazner E, Wegener OH (eds) Contrast media in computed tomography. Excerpta Medica International Congress Series 561, pp 38–45Google Scholar
  12. 12.
    Kormano M, Partanen K, Soimakallio S, Kivimäki T (1983) Dynamic contrast enhancement of the upper abdomen: effect of contrast medium and body weight. Invest Radiol 18: 364–367PubMedCrossRefGoogle Scholar
  13. 13.
    Kuikka J, Partanen K (1984) Mathematical modelling of time-density curves. The application to the diagnosis of liver cirrhosis. Invest Radiol (submitted)Google Scholar
  14. 14.
    Kunstlinger F, Federle MP, Moss AA, Marks W (1980) Computed tomography of hepatocellular carcinoma. AJR 134: 431–437PubMedGoogle Scholar
  15. 15.
    Marchai GJ, Baert AL, Wilms GE (1980) CT of noncystic liver lesions: bolus enhancement. AJR 135: 57–65Google Scholar
  16. 16.
    Moss AA, Dean PB, Axel L, Goldberg HI, Glazer GM, Friedman MA (1982) Dynamic CT of hepatic masses with intravenous and intra-arterial contrast material. AJR 138: 847–852PubMedGoogle Scholar
  17. 17.
    Paajanen H, Uotila P, Kormano M (1983) Different effect of diatrizoate and iopamidol on prostaglandin synthesis in perfused hamster lungs. Invest Radiol 18: 375–381PubMedCrossRefGoogle Scholar
  18. 18.
    Partanen KPL (1984) Dynamic CT of liver cirrhosis. Invest Radiol (in press)Google Scholar
  19. 19.
    Partanen KPL, Kormano M, Kivimäki T, Soimakallio S (1984) Comparison of iohexol and metrizamide in dynamic CT of the upper abdomen. Eur J Radiol (in press)Google Scholar
  20. 20.
    Partanen KPL, Kormano M (1984) Streak artifacts in dynamic CT. A phantom study of anterior upper abdomen. Acta Radiol (in press)Google Scholar
  21. 21.
    Tala S, Fukuda K, Aoyagi Y, Harada J (1980) CT of abdominal malignancies: dynamic approach. AJR 135: 455–461Google Scholar
  22. 22.
    Tschakert H (1980) Zeitlicher Ablauf des Dichteverhaltens von Lebermetastasen nach Kontrastmittelgabe. ROFO 133: 171–176PubMedCrossRefGoogle Scholar
  23. 23.
    Young SW, Turner RJ, Castellino RA (1980) A strategy for the contrast enhancement of malignant tumors using dynamic computed tomography and intravascular pharmacokinetics. Radiology 137: 137–147PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin, Heidelberg 1985

Authors and Affiliations

  • M. Kormano
  • K. Partanen
  • J. Kuikka

There are no affiliations available

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