Progesterone Receptors in CNS Correlated with Reproductive Behavior

  • Bruce Parsons
  • Donald Pfaff
Part of the Current Topics in Neuroendocrinology book series (CT NEUROENDOCRI, volume 5)


During the rat estrous cycle, estradiol (E2) and progesterone (P) synergize to activate and terminate feminine reproductive behavior and to induce ovulation. A 36–48 h rise in plasma E2 levels is followed by a surge in both plasma P and luteinizing hormone (LH) (Smith et al. 1975), which occurs several hours prior to the appearance of reproductive behavior on the evening of proestrus. During the initial phase of P action, P activates proceptive behaviors (Beach 1942), such as soliciting and ear-wiggling, and facilitates sexual receptivity, as measured by the frequency and quality of the lordosis posture (Ball 1937; Kuehn and Beach 1963; Hardy and DeBold 1977; Hardy 1972). Ovulation occurs during the early morning hours of estrus, and reproductive behavior disappears several hours later.


Sexual Receptivity Reproductive Behavior Gonadotropin Secretion Estradiol Benzoate Progestin Receptor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Spriger-Verlag Berlin Heidelberg 1985

Authors and Affiliations

  • Bruce Parsons
    • 1
    • 2
  • Donald Pfaff
  1. 1.Department of PharmacologyUniversity of Pennsylvania, School of MedicinePhiladelphiaUSA
  2. 2.Laboratory of Neurobiology and BehaviorRockefeller UniversityNew YorkUSA

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