Problems in Differentiation Pathways and Cellular Targets for Leukemogens Group Report
The problem of the relationship between the normal processes of cell differentiation and leukemogenic transformation was examined by tracing the normal pathways for cell differentiation to identify potential targets for the leukemogenic transformation, as reflected in the characteristics of leukemic cells and by examination of the effects of introducing or activating specific oncogenes through infection with RNA tumor viruses.
KeywordsChronic MYELOGENOUS Leukemia Rous Sarcoma Virus Hemopoietic Cell Target Cell Population Thymic Cortex
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