Gram-Negative Bacterial Infections in the Critically Ill: Pathophysiological and Clinical Aspects

  • J. Verhoef
Conference paper
Part of the Anaesthesiologie und Intensivmedizin / Anaesthesiology and Intensive Care Medicine book series (A+I, volume 167)


Bacteremia due to gram-negative rods is an important cause of morbidity and mortality, particularly in patients treated in an intensive care unit (ICU).


Disseminate Intravascular Coagulation Disseminate Intravascular Coagulation Bacterial Endotoxin Blood Clotting System Opsonic Activity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Kreger BE, Graven DE, McCabe WR (1980) Gram-negative bacteremia III: reassessment of etiology, epidemiology and ecology in 612 patients. Am J Med 88:332CrossRefGoogle Scholar
  2. 2.
    Young LS, Martin WJ, Meyer RD et al (1977) Gram-negative rode bacteremia: microbiologic, immunologic and therapeutic considerations. Ann Intern Med 86:456PubMedGoogle Scholar
  3. 3.
    van Dijk WC, Verburgh HA, van Rijswijk REN, Vos A, Verhoef J (1982) Neutrophil function ,serum opsonic activity and delayed hypersensitivity in surgical patients. Surgery, vol 92:21PubMedGoogle Scholar
  4. 4.
    van Dijk WC, Verburgh HA, van der Tol ME ,Peters R ,Verhoef J (1979) Role of Escherichia coli K capsular antigens during complement activation, C3 fixation, and opsonization. Infect Immun 25:603PubMedGoogle Scholar
  5. 5.
    Morrison DC, Ulevitch RJ (1978) The effects of bacterial endotoxins on host mediation systems. A J Pathol 93:527Google Scholar
  6. 6.
    Kalter ES, van Dijk WC, Timmerman A, Verhoef J, Bouma BN (1983) Activation of purified human plasma prekallikrein triggered by cell wall fractions of Escherichia coli and Staphylococcus aureus.J Infect Dis 148:682PubMedCrossRefGoogle Scholar
  7. 7.
    Galanos C, Luderitz O, Rietschel E, Westphal D (1977) Newer aspects of the chemistry and biology of bacterial lipopolysaccharides, with special reference to their lipid A component. In: Goodman TW (ed) Biochemistry of lipids II, vol 14 (International Review of Biochemistry). Baltimore, University Park Press, p 239Google Scholar
  8. 8.
    Ziegler EJ et al (1982) Treatment of gram-negative bacteremia and shock with human antiserum to a mutant Escherichia coli. N Engl J Med 307:1225PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1984

Authors and Affiliations

  • J. Verhoef

There are no affiliations available

Personalised recommendations