Arterial Hypoxia: Respiratory Versus Cardiovascular Dysfunction

  • H. van Aken
Conference paper
Part of the Anaesthesiologie und Intensivmedizin / Anaesthesiology and Intensive Care Medicine book series (A+I, volume 167)


To recognize the cause of hypoxia one must evaluate separately the pulmonary and haemo-dynamic changes to estimate their share in development of hypoxia. To judge the oxygenation in severely ill patients arterial PO2 alone is no reliable parameter as it is considerably influenced by the haemodynamic situation. Under physiologic conditions a detailed analysis of the cardiopulmonary system is not necessary since the PaO2 with its broad spectrum of information is adequate in the normal patient. However for patients with severe trauma and increased metabolism and sepsis or for those with a combination of cardiac or respiratory insufficiency it is of considerable importance to differentiate between cardiac and pulmonary impairment.


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  1. 1.
    Douglas ME, Downs JB, Dannemiller FJ et al (1976) Change in pulmonary venous admixture with varying inspired oxygen. Anesthesia and Analgesia 55:688–695PubMedCrossRefGoogle Scholar
  2. 2.
    Kelman GR, Nunn JF, Prys-Roberts C et al (1967) The influence of cardiac output on arterial oxygenation. A theoretical study. Br J Anaesth 39:450–458CrossRefGoogle Scholar
  3. 3.
    Kirby RR (1986) Respiratory vs cardiovascular dysfunction - How can we differentiate? ASA Refresher Course Lectures, 102Google Scholar
  4. 4.
    Nunn JF (1977) Applied respiratory physiology (2nd ed). Butterworth et CoGoogle Scholar
  5. 5.
    Van Aken H, Lawin P (1981) Der Einfluß des Herzminutenvolumens auf die arterielle Oxygenation. Anästh Intensivther Notfallmed 16:239–241PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1984

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  • H. van Aken

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